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AGN-210669 — Competitive Intelligence Brief

AGN-210669 (AGN-210669) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: TRPV1 antagonist. Area: Pain Management.

phase 2 TRPV1 antagonist TRPV1 Pain Management Small molecule Live · refreshed every 30 min

Target snapshot

AGN-210669 (AGN-210669) — Allergan. AGN-210669 is a selective inhibitor of the transient receptor potential vanilloid 1 (TRPV1) channel that reduces pain signaling in sensory neurons.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
AGN-210669 TARGET AGN-210669 Allergan phase 2 TRPV1 antagonist TRPV1
Capsaicin Topical Cream Capsaicin Topical Cream Women and Infants Hospital of Rhode Island marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
CBD CBD Stero Biotechs Ltd. marketed Cannabinoid 5-HT1A, TRPV1, GPR55, CB1 (allosteric), CB2 (allosteric)
Cannabidiol Oral Product Cannabidiol Oral Product University of Connecticut marketed Cannabinoid Multiple targets including CB1/CB2 (allosteric modulation), 5-HT1A receptor, TRPV1 channel
Capsaicin 8% Capsaicin 8% Averitas Pharma, Inc. marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
dl-Methylphenidate plus Cannabidiol dl-Methylphenidate plus Cannabidiol University of Florida marketed Combination therapy: sympathomimetic amine plus phytocannabinoid Dopamine transporter, norepinephrine transporter (methylphenidate); CB1/CB2 receptors, 5-HT1A, TRPV1 (cannabidiol)
Potassium Nitrate 2% Potassium Nitrate 2% Federal University of Uberlandia marketed Desensitizing agent Nitric oxide pathway; sensory nerve fibers (TRPV1)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (TRPV1 antagonist class)

  1. Allergan · 1 drug in this class
  2. Grünenthal GmbH · 1 drug in this class
  3. Kissei Pharmaceutical Co., Ltd. · 1 drug in this class
  4. Teva Branded Pharmaceutical Products R&D LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AGN-210669 — Competitive Intelligence Brief. https://druglandscape.com/ci/agn-210669. Accessed 2026-05-14.

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