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AGN-210669 — Competitive Intelligence Brief
phase 2
TRPV1 antagonist
TRPV1
Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
AGN-210669 (AGN-210669) — Allergan. AGN-210669 is a selective inhibitor of the transient receptor potential vanilloid 1 (TRPV1) channel that reduces pain signaling in sensory neurons.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AGN-210669 TARGET | AGN-210669 | Allergan | phase 2 | TRPV1 antagonist | TRPV1 | |
| Capsaicin Topical Cream | Capsaicin Topical Cream | Women and Infants Hospital of Rhode Island | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| CBD | CBD | Stero Biotechs Ltd. | marketed | Cannabinoid | 5-HT1A, TRPV1, GPR55, CB1 (allosteric), CB2 (allosteric) | |
| Cannabidiol Oral Product | Cannabidiol Oral Product | University of Connecticut | marketed | Cannabinoid | Multiple targets including CB1/CB2 (allosteric modulation), 5-HT1A receptor, TRPV1 channel | |
| Capsaicin 8% | Capsaicin 8% | Averitas Pharma, Inc. | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| dl-Methylphenidate plus Cannabidiol | dl-Methylphenidate plus Cannabidiol | University of Florida | marketed | Combination therapy: sympathomimetic amine plus phytocannabinoid | Dopamine transporter, norepinephrine transporter (methylphenidate); CB1/CB2 receptors, 5-HT1A, TRPV1 (cannabidiol) | |
| Potassium Nitrate 2% | Potassium Nitrate 2% | Federal University of Uberlandia | marketed | Desensitizing agent | Nitric oxide pathway; sensory nerve fibers (TRPV1) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (TRPV1 antagonist class)
- Allergan · 1 drug in this class
- Grünenthal GmbH · 1 drug in this class
- Kissei Pharmaceutical Co., Ltd. · 1 drug in this class
- Teva Branded Pharmaceutical Products R&D LLC · 1 drug in this class
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- AGN-210669 CI watch — RSS
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Cite this brief
Drug Landscape (2026). AGN-210669 — Competitive Intelligence Brief. https://druglandscape.com/ci/agn-210669. Accessed 2026-05-14.
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