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Aflibercept-mFOLFIRI3 — Competitive Intelligence Brief
phase 3
VEGF inhibitor (fusion protein) + chemotherapy combination
VEGF (vascular endothelial growth factor)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Aflibercept-mFOLFIRI3 (Aflibercept-mFOLFIRI3) — Hôpital Franco-Britannique-Fondation Cognacq-Jay. Aflibercept-mFOLFIRI3 is a combination regimen that pairs aflibercept (a VEGF trap) with modified FOLFIRI chemotherapy to inhibit angiogenesis while delivering cytotoxic chemotherapy.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Aflibercept-mFOLFIRI3 TARGET | Aflibercept-mFOLFIRI3 | Hôpital Franco-Britannique-Fondation Cognacq-Jay | phase 3 | VEGF inhibitor (fusion protein) + chemotherapy combination | VEGF (vascular endothelial growth factor) | |
| aflibercept + FOLFIRI | aflibercept + FOLFIRI | CR-CSSS Champlain-Charles-Le Moyne | marketed | VEGF inhibitor (fusion protein) + chemotherapy combination | VEGF-A, VEGF-B, PlGF (aflibercept component); topoisomerase I and thymidylate synthase (FOLFIRI component) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (VEGF inhibitor (fusion protein) + chemotherapy combination class)
- CR-CSSS Champlain-Charles-Le Moyne · 1 drug in this class
- Hôpital Franco-Britannique-Fondation Cognacq-Jay · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Aflibercept-mFOLFIRI3 — Competitive Intelligence Brief. https://druglandscape.com/ci/aflibercept-mfolfiri3. Accessed 2026-05-16.
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