Who are Vegf Trap's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Vabysmo, Beovu, Macugen, Avastin, Macugen, intra-vitreal injection of Ranibizumab.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Vegf Trap — Competitive Intelligence Brief

Vegf Trap (AFLIBERCEPT) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Vascular Endothelial Growth Factor Inhibitor. Area: Oncology.

marketed Vascular Endothelial Growth Factor Inhibitor Vascular endothelial growth factor A Oncology Recombinant protein Live · refreshed every 30 min

Target snapshot

Vegf Trap (AFLIBERCEPT) — Regeneron.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Vegf Trap TARGET	AFLIBERCEPT	Regeneron	marketed	Vascular Endothelial Growth Factor Inhibitor	Vascular endothelial growth factor A	2011-01-01
Vabysmo	FARICIMAB	Roche	marketed		Vascular endothelial growth factor A	2022-01-01
Beovu	BROLUCIZUMAB	Novartis	marketed		Vascular endothelial growth factor A	2019-01-01
Macugen	pegaptanib	Bausch Health	marketed		Vascular endothelial growth factor A	2004-01-01
Avastin	bevacizumab	Roche	marketed	Vascular Endothelial Growth Factor Inhibitor [EPC]	Vascular endothelial growth factor A	2004-01-01
Macugen	EYE001	Valeant Pharms Llc	marketed		Vascular endothelial growth factor A	2004-01-01
intra-vitreal injection of Ranibizumab	intra-vitreal injection of Ranibizumab	Ain Shams University	marketed	VEGF-A inhibitor (monoclonal antibody fragment)	VEGF-A (Vascular Endothelial Growth Factor A)

Recent regulatory actions (last 90 days)

2026-04-09 — Vabysmo · FDA · approved · US · Roche

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Vascular Endothelial Growth Factor Inhibitor class)

Regeneron · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Vegf Trap — Competitive Intelligence Brief. https://druglandscape.com/ci/aflibercept. Accessed 2026-05-13.

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