Who are ADX415's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): RNF, KI1106 4g, QD, HP-802-247, SCTB14, TAK-667, TBI-1301.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

ADX415 — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

ADX415 (ADX415) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CD47 inhibitor. Area: Oncology.

phase 2 CD47 inhibitor CD47 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

ADX415 (ADX415) — Addrenex Pharmaceuticals, Inc.. ADX415 is a monoclonal antibody targeting CD47.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
ADX415 TARGET	ADX415	Addrenex Pharmaceuticals, Inc.	phase 2	CD47 inhibitor	CD47
RNF	RNF	Merck KGaA, Darmstadt, Germany	phase 3	CD47/SIRPα inhibitor	CD47
KI1106 4g, QD	KI1106 4g, QD	Kuhnil Pharmaceutical Co., Ltd.	phase 3	CD47/SIRPα inhibitor	CD47/SIRPα axis
HP-802-247	HP-802-247	Healthpoint	phase 3	CD47 antibody	CD47
SCTB14	SCTB14	Sinocelltech Ltd.	phase 3	CD47/SIRPα axis inhibitor	CD47/SIRPα axis
TAK-667	TAK-667	Takeda	phase 3	CD47 antibody	CD47
TBI-1301	TBI-1301	Takara Bio Inc.	phase 3	CD47 antibody	CD47

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CD47 inhibitor class)

Addrenex Pharmaceuticals, Inc. · 1 drug in this class
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. · 1 drug in this class
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company · 1 drug in this class
Q32 Bio Inc. · 1 drug in this class
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ADX415 — Competitive Intelligence Brief. https://druglandscape.com/ci/adx415. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing