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Active hypertension medical therapy — Competitive Intelligence Brief
phase 1
Angiotensin II receptor antagonist
AT1 receptor
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Active hypertension medical therapy (Active hypertension medical therapy) — Verve Medical, Inc. Blocks the action of angiotensin II at the AT1 receptor
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Active hypertension medical therapy TARGET | Active hypertension medical therapy | Verve Medical, Inc | phase 1 | Angiotensin II receptor antagonist | AT1 receptor | |
| Edarbi | AZILSARTAN MEDOXOMIL | Arbor Pharms Ireland | marketed | Angiotensin 2 Receptor Blocker | AT1 receptor | 2011-01-01 |
| Cozaar | losartan | Merck & Co. | marketed | ARB (Angiotensin II receptor blocker) | AT1 receptor | 1995-04-14 |
| Lenvatinib + losartan | Lenvatinib + losartan | Second Affiliated Hospital of Xi'an Jiaotong University | marketed | Multi-targeted tyrosine kinase inhibitor + angiotensin II receptor antagonist | FGFR, VEGFR, RET (lenvatinib); AT1 receptor (losartan) | |
| olmesartan medoxomil+probenecid | olmesartan medoxomil+probenecid | Central South University | marketed | Angiotensin II receptor blocker + uricosuric agent | AT1 receptor (angiotensin II type 1 receptor); uric acid transporter (URAT1) | |
| Diovan (Valsartan) | Diovan (Valsartan) | Bayer | marketed | Angiotensin II receptor blocker (ARB) | AT1 receptor (Angiotensin II type 1 receptor) | |
| Candesartan cilexetil / hydrochlorothiazide | Candesartan cilexetil / hydrochlorothiazide | Takeda | marketed | Angiotensin II receptor antagonist / thiazide diuretic combination | AT1 receptor (angiotensin II type 1 receptor); sodium-chloride cotransporter |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Angiotensin II receptor antagonist class)
- Abbott · 1 drug in this class
- Ahn-Gook Pharmaceuticals Co.,Ltd · 1 drug in this class
- Ain Shams University · 1 drug in this class
- Boryung Pharmaceutical Co., Ltd · 1 drug in this class
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company · 1 drug in this class
- EMS · 1 drug in this class
- Kaohsiung Medical University Chung-Ho Memorial Hospital · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- St. Joseph's Hospital and Medical Center, Phoenix · 1 drug in this class
- Tanabe Pharma Corporation · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Active hypertension medical therapy — Competitive Intelligence Brief. https://druglandscape.com/ci/active-hypertension-medical-therapy. Accessed 2026-05-16.
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