Who are Actinomycin-D's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): CEDAZURIDINE, Dacogen, Vidaza, Zymar, Hepsera, Eloxatin.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Actinomycin-D — Competitive Intelligence Brief

Actinomycin-D (Actinomycin-D) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: DNA intercalating agent. Area: Oncology.

marketed DNA intercalating agent DNA Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Actinomycin-D (Actinomycin-D) — Peking Union Medical College Hospital. Actinomycin-D intercalates into DNA and inhibits RNA polymerase, preventing transcription and leading to cell death.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Actinomycin-D TARGET	Actinomycin-D	Peking Union Medical College Hospital	marketed	DNA intercalating agent	DNA
CEDAZURIDINE	CEDAZURIDINE		marketed	Nucleoside Metabolic Inhibitor [EPC]	DNA methyltransferase	2020-01-01
Dacogen	decitabine	Sun Pharma	marketed	Nucleoside Metabolic Inhibitor [EPC]	DNA (cytosine-5)-methyltransferase 1	2006-01-01
Vidaza	azacitidine	Bristol-Myers Squibb	marketed	Nucleoside Metabolic Inhibitor [EPC]	DNA (cytosine-5)-methyltransferase 1	2004-01-01
Zymar	GATIFLOXACIN	Allergan	marketed		DNA gyrase, DNA gyrase, DNA gyrase subunit A	2003-01-01
Hepsera	ADEFOVIR DIPIVOXIL	Gilead Sciences	marketed	Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor	DNA polymerase subunit gamma-1	2002-01-01
Eloxatin	Oxaliplatin	Yakult Honsha	marketed	Platinum-based chemotherapy agent	DNA	2002-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-05-14 — Vidaza · 12053482 · Method of Use · US
2029-05-14 — Vidaza · 11571436 · Formulation · US
2030-06-03 — Vidaza · 8846628 · Formulation · US

Sponsor landscape (DNA intercalating agent class)

Peking Union Medical College Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Actinomycin-D — Competitive Intelligence Brief. https://druglandscape.com/ci/actinomycin-d. Accessed 2026-05-13.

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