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acamprosate (Campral) — Competitive Intelligence Brief
marketed
NMDA receptor modulator
NMDA receptor (glutamate); GABA system
Psychiatry / Addiction Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
acamprosate (Campral) (acamprosate (Campral)) — University of North Carolina, Chapel Hill. Acamprosate modulates glutamate and GABA neurotransmission to restore neurochemical balance disrupted by chronic alcohol use.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| acamprosate (Campral) TARGET | acamprosate (Campral) | University of North Carolina, Chapel Hill | marketed | NMDA receptor modulator | NMDA receptor (glutamate); GABA system | |
| Placebo-matching Rapastinel | Placebo-matching Rapastinel | Naurex, Inc, an affiliate of Allergan plc | phase 3 | NMDA receptor modulator | NMDA receptor (N-methyl-D-aspartate receptor) | |
| Nerinetide (NA-1) | Nerinetide (NA-1) | NoNO Inc. | phase 3 | NMDA receptor modulator / Neuroprotective peptide | PSD-95 (postsynaptic density protein 95) | |
| NRX-101 Oral Capsule | NRX-101 Oral Capsule | NeuroRx, Inc. | phase 3 | Fixed-dose combination (NMDA receptor modulator + atypical antipsychotic) | NMDA receptor (d-cycloserine component); dopamine D2 receptor and serotonin 5-HT7 receptor (lurasidone component) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NMDA receptor modulator class)
- Naurex, Inc, an affiliate of Allergan plc · 1 drug in this class
- University of North Carolina, Chapel Hill · 1 drug in this class
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Cite this brief
Drug Landscape (2026). acamprosate (Campral) — Competitive Intelligence Brief. https://druglandscape.com/ci/acamprosate-campral. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing