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ABT-450/ritonavir — Competitive Intelligence Brief

ABT-450/ritonavir (ABT-450/ritonavir) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Hepatitis C virus NS3/4A protease inhibitor. Area: Virology / Hepatology.

phase 3 Hepatitis C virus NS3/4A protease inhibitor HCV NS3/4A serine protease Virology / Hepatology Small molecule Live · refreshed every 30 min

Target snapshot

ABT-450/ritonavir (ABT-450/ritonavir) — AbbVie (prior sponsor, Abbott). ABT-450 is a hepatitis C virus NS3/4A protease inhibitor that blocks viral replication, boosted by ritonavir to increase drug levels.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
ABT-450/ritonavir TARGET ABT-450/ritonavir AbbVie (prior sponsor, Abbott) phase 3 Hepatitis C virus NS3/4A protease inhibitor HCV NS3/4A serine protease
Daclatasvir plus Asunaprevir Daclatasvir plus Asunaprevir Myeong Jun Song marketed Direct-acting antiviral combination (NS5A inhibitor + NS3/4A protease inhibitor) HCV NS5A protein and HCV NS3/4A serine protease
Elbasvir/Grazoprevir Elbasvir/Grazoprevir University of Florence marketed Direct-acting antiviral (DAA) combination; NS5A inhibitor + NS3/4A protease inhibitor HCV NS5A protein and HCV NS3/4A serine protease
Elbasvir / Grazoprevir Oral Tablet [Zepatier] Elbasvir / Grazoprevir Oral Tablet [Zepatier] University of Maryland, Baltimore marketed Direct-acting antiviral (DAA) combination HCV NS5A protein and HCV NS3/4A serine protease
Viekira Pak ± ribavirin Viekira Pak ± ribavirin Massachusetts General Hospital marketed Direct-acting antiviral (DAA) combination HCV NS5A protein, HCV NS3/4A serine protease
ABT-450/r/ABT-267, ABT-333 ABT-450/r/ABT-267, ABT-333 AbbVie (prior sponsor, Abbott) phase 3 HCV protease inhibitor and non-nucleoside polymerase inhibitor combination HCV NS3/4A serine protease and NS5B RNA-dependent RNA polymerase
BMS-650032 (Asunaprevir) BMS-650032 (Asunaprevir) Bristol-Myers Squibb phase 3 HCV NS3 protease inhibitor HCV NS3/4A serine protease

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Hepatitis C virus NS3/4A protease inhibitor class)

  1. AbbVie (prior sponsor, Abbott) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ABT-450/ritonavir — Competitive Intelligence Brief. https://druglandscape.com/ci/abt-450-ritonavir. Accessed 2026-05-17.

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