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ABT-450/r/ABT-267 — Competitive Intelligence Brief
phase 3
Hepatitis C virus protease inhibitor and NS5A inhibitor combination
HCV NS3/4A protease and NS5A protein
Virology/Hepatology
Small molecule
Live · refreshed every 30 min
Target snapshot
ABT-450/r/ABT-267 (ABT-450/r/ABT-267) — AbbVie. ABT-450/r/ABT-267 is a fixed-dose combination of a hepatitis C virus NS3/4A protease inhibitor (ABT-450) boosted with ritonavir and an NS5A inhibitor (ABT-267) that blocks viral replication.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ABT-450/r/ABT-267 TARGET | ABT-450/r/ABT-267 | AbbVie | phase 3 | Hepatitis C virus protease inhibitor and NS5A inhibitor combination | HCV NS3/4A protease and NS5A protein | |
| Glecaprevir and Pibrentasvir | Glecaprevir and Pibrentasvir | Massachusetts General Hospital | marketed | Direct-acting antiviral combination (NS3/4A protease inhibitor + NS5A inhibitor) | HCV NS3/4A protease and NS5A protein | |
| Grazaoprevir/Elbasavir | Grazaoprevir/Elbasavir | The HIV Netherlands Australia Thailand Research Collaboration | marketed | Direct-acting antiviral (DAA) combination | HCV NS3/4A protease and NS5A protein | |
| Grazoprevir/Elbasvir | Grazoprevir/Elbasvir | Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba | marketed | Direct-acting antiviral (DAA) combination | HCV NS3/4A protease and NS5A protein | |
| glecaprevir/pibrentasvir tablets | glecaprevir/pibrentasvir tablets | Raymond T. Chung, MD | marketed | Direct-acting antiviral combination (NS3/4A protease inhibitor + NS5A inhibitor) | HCV NS3/4A protease and NS5A protein | |
| Post-transplant Grazoprevir and Elbasvir | Post-transplant Grazoprevir and Elbasvir | University of Maryland, Baltimore | marketed | Direct-acting antiviral (DAA) combination | HCV NS3/4A protease and NS5A protein | |
| Glecaprevir / Pibrentasvir Oral Tablet [Mavyret] | Glecaprevir / Pibrentasvir Oral Tablet [Mavyret] | Massachusetts General Hospital | marketed | Direct-acting antiviral (DAA) combination | HCV NS3/4A protease and NS5A protein |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Hepatitis C virus protease inhibitor and NS5A inhibitor combination class)
- AbbVie · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). ABT-450/r/ABT-267 — Competitive Intelligence Brief. https://druglandscape.com/ci/abt-450-r-abt-267. Accessed 2026-05-18.
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