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AB-106, Itraconazole — Competitive Intelligence Brief

AB-106, Itraconazole (AB-106, Itraconazole) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Azole antifungal. Area: Infectious Disease.

phase 1 Azole antifungal Cytochrome P450 14α-demethylase Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

AB-106, Itraconazole (AB-106, Itraconazole) — Nuvation Bio Inc.. Inhibits fungal cytochrome P450 14α-demethylase

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
AB-106, Itraconazole TARGET AB-106, Itraconazole Nuvation Bio Inc. phase 1 Azole antifungal Cytochrome P450 14α-demethylase
slow itraconazole tablet slow itraconazole tablet University of Maryland, Baltimore marketed Triazole antifungal Fungal cytochrome P450 14α-demethylase (CYP51)
Diflucan (fluconazole) Diflucan (fluconazole) Pfizer marketed Triazole antifungal Fungal cytochrome P450 14α-demethylase (CYP51)
Vfend (voriconazole) tablet Vfend (voriconazole) tablet Seoul National University Hospital marketed Triazole antifungal Cytochrome P450 14α-demethylase (CYP51)
ITCZ-IV ITCZ-IV Janssen Pharmaceutical K.K. phase 3 Triazole antifungal Fungal cytochrome P450 14α-demethylase (CYP51)
Vivjoa OTESECONAZOLE Mycovia Pharms marketed Azole Antifungal [EPC] Cytochrome P450 3A4 2022-01-01
Cresemba ISAVUCONAZONIUM Astellas Pharma marketed Azole Antifungal ATP-binding cassette sub-family G member 2 2015-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Azole antifungal class)

  1. Pfizer · 3 drugs in this class
  2. Elion Therapeutics, Inc. · 1 drug in this class
  3. Hadassah Medical Organization · 1 drug in this class
  4. Hatem AbuHashim · 1 drug in this class
  5. Janssen Pharmaceutical K.K. · 1 drug in this class
  6. Jiangsu Aosaikang Pharmaceutical Co., Ltd. · 1 drug in this class
  7. Military Hospital of Tunis · 1 drug in this class
  8. Mycovia Pharmaceuticals Inc. · 1 drug in this class
  9. Nuvation Bio Inc. · 1 drug in this class
  10. Purdue Pharma LP · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AB-106, Itraconazole — Competitive Intelligence Brief. https://druglandscape.com/ci/ab-106-itraconazole. Accessed 2026-05-16.

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