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AB-106, digoxin — Competitive Intelligence Brief

AB-106, digoxin (AB-106, digoxin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Cardiac glycoside. Area: Cardiovascular.

phase 1 Cardiac glycoside Sodium-potassium ATPase Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

AB-106, digoxin (AB-106, digoxin) — Nuvation Bio Inc.. Digoxin inhibits the sodium-potassium ATPase pump.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
AB-106, digoxin TARGET AB-106, digoxin Nuvation Bio Inc. phase 1 Cardiac glycoside Sodium-potassium ATPase
DIGOXIN DIGOXIN marketed Cardiac Glycoside [EPC] 1975-01-01
Lanoxin digoxin Generic (originally Burroughs Wellcome/GSK) marketed Cardiac Glycoside [EPC] Nuclear receptor ROR-gamma, Signal transducer and activator of transcription 3, Potassium voltage-gated channel subfamily H member 2 1954-01-01
Rate-control therapy Rate-control therapy Our Lady of the Lake Hospital marketed AV nodal blocking agents (beta-blockers, non-dihydropyridine calcium channel blockers, or cardiac glycosides) AV nodal conduction (multiple targets depending on agent: beta-1 adrenergic receptors, L-type calcium channels, or adenosine receptors)
Cinobufacini Injection Cinobufacini Injection Dongfang Hospital Beijing University of Chinese Medicine marketed Natural product bufadienolide; cardiac glycoside analog Na+/K+-ATPase; multiple apoptotic pathways
Intra-amniotic injection of DIGOXIN Intra-amniotic injection of DIGOXIN Meir Medical Center phase 3 Cardiac glycoside Na+/K+-ATPase
Magnesium sulfate and then Digoxin Magnesium sulfate and then Digoxin Sunnybrook Health Sciences Centre phase 3 Electrolyte supplement and cardiac glycoside combination Na+/K+-ATPase (digoxin); magnesium-dependent ion channels and enzymes (magnesium sulfate)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Cardiac glycoside class)

  1. Advenchen Laboratories, LLC · 1 drug in this class
  2. Meir Medical Center · 1 drug in this class
  3. Nuvation Bio Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AB-106, digoxin — Competitive Intelligence Brief. https://druglandscape.com/ci/ab-106-digoxin. Accessed 2026-05-13.

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