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AB-106, digoxin — Competitive Intelligence Brief
phase 1
Cardiac glycoside
Sodium-potassium ATPase
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
AB-106, digoxin (AB-106, digoxin) — Nuvation Bio Inc.. Digoxin inhibits the sodium-potassium ATPase pump.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AB-106, digoxin TARGET | AB-106, digoxin | Nuvation Bio Inc. | phase 1 | Cardiac glycoside | Sodium-potassium ATPase | |
| DIGOXIN | DIGOXIN | marketed | Cardiac Glycoside [EPC] | 1975-01-01 | ||
| Lanoxin | digoxin | Generic (originally Burroughs Wellcome/GSK) | marketed | Cardiac Glycoside [EPC] | Nuclear receptor ROR-gamma, Signal transducer and activator of transcription 3, Potassium voltage-gated channel subfamily H member 2 | 1954-01-01 |
| Rate-control therapy | Rate-control therapy | Our Lady of the Lake Hospital | marketed | AV nodal blocking agents (beta-blockers, non-dihydropyridine calcium channel blockers, or cardiac glycosides) | AV nodal conduction (multiple targets depending on agent: beta-1 adrenergic receptors, L-type calcium channels, or adenosine receptors) | |
| Cinobufacini Injection | Cinobufacini Injection | Dongfang Hospital Beijing University of Chinese Medicine | marketed | Natural product bufadienolide; cardiac glycoside analog | Na+/K+-ATPase; multiple apoptotic pathways | |
| Intra-amniotic injection of DIGOXIN | Intra-amniotic injection of DIGOXIN | Meir Medical Center | phase 3 | Cardiac glycoside | Na+/K+-ATPase | |
| Magnesium sulfate and then Digoxin | Magnesium sulfate and then Digoxin | Sunnybrook Health Sciences Centre | phase 3 | Electrolyte supplement and cardiac glycoside combination | Na+/K+-ATPase (digoxin); magnesium-dependent ion channels and enzymes (magnesium sulfate) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Cardiac glycoside class)
- Advenchen Laboratories, LLC · 1 drug in this class
- Meir Medical Center · 1 drug in this class
- Nuvation Bio Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AB-106, digoxin — Competitive Intelligence Brief. https://druglandscape.com/ci/ab-106-digoxin. Accessed 2026-05-13.
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