Last reviewed · How we verify
131-I-TM-601 — Competitive Intelligence Brief
phase 2
Targeted alpha-particle therapy
CD47
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
131-I-TM-601 (131-I-TM-601) — TransMolecular. 131-I-TM-601 is a targeted alpha-particle therapy that selectively targets and destroys cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| 131-I-TM-601 TARGET | 131-I-TM-601 | TransMolecular | phase 2 | Targeted alpha-particle therapy | CD47 | |
| Treatment Choice (TC) | Treatment Choice (TC) | Astex Pharmaceuticals, Inc. | phase 3 | SIRPα inhibitor | CD47 | |
| TAK-667 | TAK-667 | Takeda | phase 3 | CD47 antibody | CD47 | |
| MB-102 DMID | MB-102 DMID | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | phase 3 | monoclonal antibody | CD47 | |
| SCTB14 | SCTB14 | Sinocelltech Ltd. | phase 3 | CD47/SIRPα axis inhibitor | CD47/SIRPα axis | |
| KI1106 4g, QD | KI1106 4g, QD | Kuhnil Pharmaceutical Co., Ltd. | phase 3 | CD47/SIRPα inhibitor | CD47/SIRPα axis | |
| RNF | RNF | Merck KGaA, Darmstadt, Germany | phase 3 | CD47/SIRPα inhibitor | CD47 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Targeted alpha-particle therapy class)
- TransMolecular · 1 drug in this class
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Cite this brief
Drug Landscape (2026). 131-I-TM-601 — Competitive Intelligence Brief. https://druglandscape.com/ci/131-i-tm-601. Accessed 2026-05-14.
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