Last reviewed · How we verify
NCT07536867: SPSIP-RIB
Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block for Postoperative Analgesia Following Breast Cancer Surgery With Axillary Lymph Node Dissection: A Randomized Controlled Trial
NA trial testing Serratus posterior superior intercostal plane block in Breast Cancer in 50 participants. Not yet recruiting.
30 March 2027
Quick facts
| Lead sponsor | Antalya City Hospital |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 30 March 2026 |
| Primary completion | 30 March 2027 |
| Estimated completion | 30 April 2027 |
Drugs / interventions tested
- Serratus posterior superior intercostal plane block — full drug profile →
- Rhomboid intercostal plane block — full drug profile →
Conditions studied
- Breast Cancer — all drugs for Breast Cancer →
- Lymph Node Dissection — all drugs for Lymph Node Dissection →
- Postoperative Pain — all drugs for Postoperative Pain →
- Mastectomy — all drugs for Mastectomy →
Sponsor
Antalya City Hospital
Who can join
Adults 18 to 65, female only, with Breast Cancer or Lymph Node Dissection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) and Rhomboid Intercostal Block in patients undergoing Breast Cancer Surgery With Axillary Lymph Node Dissection. The primary outcome is Visual Analog Scale (VAS) during the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block performance time, block-related and systemic side effects (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection), Patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07536867
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Serratus posterior superior intercostal plane block
Trials testing the same drug.
- NCT07467291 — SPSIP Block vs SAP Block for Post-VATS Pain · NA · recruiting
- NCT07278050 — Interscalene Block vs Serratus Posterior Superior Intercostal Plane Block · NA · recruiting
- NCT07238621 — Postoperative Analgesic Efficacy of SPSIPB in Anterior Cervical Discectomy · NA · active not recruiting
- NCT06997601 — Serratus Posterior Superior Intercostal Plane Block Versus Suprascapular Nerve Block and Axillary Nerve Block for Analge · NA · completed
- NCT07426692 — Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block for Postoperative Analg · NA · completed
Other recruiting trials for Breast Cancer
Currently open trials in the same condition.
- NCT06148038 — CBD for Breast Cancer Primary Tumors · Phase 1 · recruiting
- NCT07405801 — A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus R · Phase 2 · recruiting
- NCT07285993 — Detection and Outcomes in Metastatic Invasive Lobular Breast Cancer Through Novel F-18 FAP PET · Phase 2 · recruiting
- NCT07510698 — Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer · NA · recruiting
- NCT06768931 — Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07536867 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Antalya City Hospital
- Last refreshed: 17 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07536867.
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