Impact of PDT and Topical Corticosteroids on Taste Perception in Patients With OLP

NCT07536737 NA COMPLETED

Oral lichen planus (OLP) is a chronic inflammatory disease that affects the lining of the mouth and may cause pain, burning sensations, and discomfort. Some patients also report changes in their ability to taste different flavors. The aim of this study is to compare two commonly used treatments for OLP: photodynamic therapy (PDT) and topical corticosteroids. PDT is a light-based treatment that uses a special gel applied to the affected areas, followed by illumination with a medical light device. Topical corticosteroids are anti-inflammatory medications applied directly to the lesions. Participants in this study are randomly assigned to receive one of these two treatments. Before starting therapy and immediately after its completion, patients undergo a simple taste test using special strips that assess the ability to recognize sweet, sour, salty, and bitter tastes. In addition, the size of oral lesions and the intensity of symptoms such as pain or burning are evaluated. The results of this study may help to better understand how different treatments for oral lichen planus affect taste perception and overall patient well-being, and may support the selection of the most appropriate therapy in clinical practice.

Details

Lead sponsor	Medical University of Bialystok
Phase	NA
Status	COMPLETED
Enrolment	65
Start date	Thu Sep 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Jul 10 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Oral Lichen Planus

Interventions

• 5-Amino Levulinic Acid
• Clobetasol Propionate 0.05% Cream

Countries

Poland