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NCT07532759
Impact of Intraoperative PTCD Catheter Retention Versus Removal on Postoperative Short-term Outcomes After Pancreaticoduodenectomy in Obstructive Jaundice
NA trial testing PTCD Catheter Removal in Obstructive Jaundice in 100 participants. Not yet recruiting.
28 February 2028
Quick facts
| Lead sponsor | Xu'an Wang |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 May 2026 |
| Primary completion | 28 February 2028 |
| Estimated completion | 30 April 2028 |
Drugs / interventions tested
- PTCD Catheter Removal
- PTCD Catheter Retention
Conditions studied
- Obstructive Jaundice — all drugs for Obstructive Jaundice →
- Pancreatic Head Cancer — all drugs for Pancreatic Head Cancer →
- Periampullary Neoplasms — all drugs for Periampullary Neoplasms →
- Biliary Tract Neoplasms — all drugs for Biliary Tract Neoplasms →
Sponsor
Xu'an Wang
Who can join
Adults 18 to 85, any sex, with Obstructive Jaundice or Pancreatic Head Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pancreaticoduodenectomy (PD) is a complex surgical procedure commonly performed for tumors of the pancreatic head and periampullary region. Many patients present with obstructive jaundice and undergo preoperative percutaneous transhepatic cholangial drainage (PTCD) to relieve biliary obstruction. However, there is currently no consensus on whether the PTCD catheter should be removed or retained during surgery. This multicenter, prospective randomized controlled trial aims to compare two intraoperative strategies: removal versus retention of the PTCD catheter during PD. Participants will be randomly assigned to either group. The study will evaluate whether these different approaches influence postoperative outcomes, particularly major complications such as bile leak and severe postoperative morbidity within 90 days after surgery. In addition to complications, the study will assess recovery after surgery, including return of gastrointestinal function, length of hospital stay, and quality of recovery, as well as laboratory indicators of liver function and inflammation. The results of this study are expected to provide evidence to guide surgical decision-making regarding PTCD management during PD and to improve patient outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07532759
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
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- NCT06541340 — A New Strategy for Preoperative Drainage of Resectable Pancreatic Head Cancer Combined Severe Obstructive Jaundice · NA · recruiting
- NCT06456476 — Patients With Obstructive Jaundice In Sohag University Hospital · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07532759 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xu'an Wang
- Last refreshed: 16 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07532759.
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