Who is sponsoring NCT07528118?

NCT07528118 is sponsored by Sargodha Medical College.

What drugs are being tested in NCT07528118?

Interventions in NCT07528118: Inj Aminophylline 100mg with Inj Acetaminophen 1000mg in 100ml Normal Saline, Inj Aminophylline 100mg , with 0.1mg/kg Dexamethasone in 100ml Normal Saline.

What condition does NCT07528118 study?

NCT07528118 studies Post Dural Puncture Headache.

Is NCT07528118 still recruiting?

NCT07528118 is currently completed. Last updated 14 April 2026.

Last reviewed 2026-04-14 · How we verify

NCT07528118: PDPH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Acetaminophen With Aminophylline and Aminophylline With Dexamethasone for Prophylaxis of PDPH in Patients With History of PDPH.

Completed Phase 2 Last updated 14 April 2026

What this trial tests

Phase 2 trial testing Inj Aminophylline 100mg with Inj Acetaminophen 1000mg in 100ml Normal Saline in Post Dural Puncture Headache in 50 participants. Completed in 8 July 2024.

Timeline

1 August 2023

Primary endpoint
2 June 2024

8 July 2024

Quick facts

Lead sponsor	Sargodha Medical College
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	50
Start date	1 August 2023
Primary completion	2 June 2024
Estimated completion	8 July 2024
Sites	1 location across Pakistan

Drugs / interventions tested

Inj Aminophylline 100mg with Inj Acetaminophen 1000mg in 100ml Normal Saline
Inj Aminophylline 100mg , with 0.1mg/kg Dexamethasone in 100ml Normal Saline

Conditions studied

Post Dural Puncture Headache — all drugs for Post Dural Puncture Headache →

Sponsor

Sargodha Medical College

Who can join

Adults 18 to 40, any sex, with Post Dural Puncture Headache. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is hypothesized that there is a difference between intravenously administered aminophylline with intravenous acetaminophen and intravenously administered aminophylline with dexamethasone for prevention of and reducing severity of PDPH.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other Sargodha Medical College trials

Trials by the same sponsor.

NCT07269678 — Comparative Study of Two Infraclavicular Block Approaches in Forearm Surgery · NA · completed
NCT07418086 — Supraclavicular Block vs Bier's Block for Forearm Trauma Surgery · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07528118 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sargodha Medical College
Last refreshed: 14 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07528118.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing