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NCT07526883
The Effect of Non-Surgical Periodontal Treatment on Systemic Inflammatory Markers and Lipid Profile in Young Adults With Severe Periodontitis
NA trial testing Non-surgical periodontal treatment in Periodontitis, Aggressive in 50 participants. Completed in 1 June 2010.
1 December 2009
Quick facts
| Lead sponsor | Istanbul University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 July 2006 |
| Primary completion | 1 December 2009 |
| Estimated completion | 1 June 2010 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Non-surgical periodontal treatment
Conditions studied
- Periodontitis, Aggressive — all drugs for Periodontitis, Aggressive →
Sponsor
Istanbul University
Who can join
Adults 19 to 36, any sex, with Periodontitis, Aggressive. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical study was to evaluate whether non-surgical treatment for severe periodontitis (gum disease) could improve body-wide inflammation and blood fat levels in young adults with severe periodontitis. The main questions it aimed to answer were: Did non-surgical periodontal treatment improve gum health in young adults with severe periodontitis? Did non-surgical periodontal treatment change body-wide inflammation and blood fat levels after treatment? Researchers compared participants with severe periodontitis to healthy participants without periodontitis. Participants with severe periodontitis: * Received oral hygiene instructions, deep cleaning below the gumline, root surface cleaning, and removal of teeth that could not be saved * Had full-mouth gum examinations * Provided blood samples at the start of the study and again at 2 and 6 months after treatment Healthy participants: * Had gum examinations * Provided blood samples for comparison at the start of the study
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07526883
- Europe PMC full search
- ASCO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07526883 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul University
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07526883.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing