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NCT07524153
Diode Laser and S100A8 in Peri-Implantitis
trial in Periimplant Diseases in 39 participants. Completed in 10 October 2025.
1 June 2025
Quick facts
| Lead sponsor | Kırıkkale University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 39 |
| Start date | 1 January 2025 |
| Primary completion | 1 June 2025 |
| Estimated completion | 10 October 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Periimplant Diseases — all drugs for Periimplant Diseases →
- S100A8 — all drugs for S100A8 →
- Biomarkers — all drugs for Biomarkers →
- Calprotectin — all drugs for Calprotectin →
Sponsor
Kırıkkale University
Who can join
Adults 30 to 65, any sex, with Periimplant Diseases or S100A8. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Purpose: The aim of this study was to compare the effectiveness of diode laser and combined treatment protocols, applied in addition to mechanical debridement, in the treatment of peri-implantitis on clinical periodontal parameters and S100A8 levels in peri-implant sulcus fluid (PISF). Methods: A total of 39 patients diagnosed with peri-implantitis were divided into three groups based on the treatment protocols used: Mechanical Debridement, Diode Laser, and Combined Treatment. Probing depth, clinical attachment level, modified plaque index, gingival index, and PISF volume measurements were recorded at baseline and at weeks 4 and 12. S100A8 levels in PISF samples were measured by ELISA.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07524153
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Periimplant Diseases
Currently open trials in the same condition.
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Other Kırıkkale University trials
Trials by the same sponsor.
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- NCT07451860 — Chronic Total Occlusion and Triglyceride-Glucose Index · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07524153 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kırıkkale University
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07524153.
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