NCT07518524: Fast Track

Ultra Fast-Track vs Fast-Track Protocols in Off-Pump and Minimally Invasive Valve Cardiac Surgery

Recruiting now NA Last updated 8 April 2026

What this trial tests

NA trial testing Fast Track Cardiac Anesthesia (FTCA) in Cardiac Surgery in 50 participants. Currently enrolling.

Timeline

18 June 2025

Primary endpoint
1 March 2026

15 December 2027

Quick facts

Lead sponsor	Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	50
Start date	18 June 2025
Primary completion	1 March 2026
Estimated completion	15 December 2027
Sites	1 location across Italy

Drugs / interventions tested

• Fast Track Cardiac Anesthesia (FTCA)
• Ultra Fast Track Cardiac Anesthesia (UFTCA)

Conditions studied

• Cardiac Surgery — all drugs for Cardiac Surgery →

Sponsor

Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano

Who can join

18 and older, any sex, with Cardiac Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Fast-track cardiac anesthesia (FTCA) has gained significant popularity over the past decades due to its potential to reduce healthcare costs and optimize the use of medical resources. This approach has led anesthesiologists to reconsider the traditional model of cardiac anesthesia, known as Conventional Cardiac Anesthesia (CCA), which historically relied on the administration of high-dose opioids to ensure adequate hemodynamic stability and prolonged postoperative analgesia, thereby reducing the incidence of myocardial ischemia.

One of the primary goals of fast-track cardiac anesthesia is early tracheal extubation. Increasing evidence demonstrates that early extubation is associated with a reduction in the length of stay in the intensive care unit (ICU) and overall hospital length of stay, resulting in significant cost savings without negatively affecting patients' clinical outcomes. In contrast, prolonged mechanical ventilation has been shown to have a substantial economic impact and, more importantly, is associated with higher in-hospital mortality and reduced long-term survival, including decreased five-year survival rates. The Ultra Fast Track protocol, which involves extubation directly in the operating room, is currently less commonly used. However, it may further reduce postoperative mechanical ventilation time and the incidence of pulmonary complications, potentially leading to an additional reduction in hospital length of stay. The aim of this study is to compare the Fast Track and Ultra Fast Track protocols in order to evaluate differences in the incidence of respiratory, cardiac, renal, septic, and neurological complications. Postoperative pain will also be assessed using the Numeric Rating Scale (NRS), as well as the incidence of postoperative nausea and vomiting (PONV).

Publications & conference data

No peer-reviewed publications indexed yet for this trial.