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NCT07517783
"Comparison of Clip-Based and Clipless Laparoscopic Gallbladder Surgery in Controlling Bleeding"
NA trial testing clips in Laparoscopic Cholecystectomy Surgery in 114 participants. Completed in 30 June 2024.
28 May 2024
Quick facts
| Lead sponsor | Wah Medical college , POF hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 114 |
| Start date | 1 January 2024 |
| Primary completion | 28 May 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- clips
- ligasure
Conditions studied
- Laparoscopic Cholecystectomy Surgery — all drugs for Laparoscopic Cholecystectomy Surgery →
Sponsor
Wah Medical college , POF hospital
Who can join
Adults 18 to 60, any sex, with Laparoscopic Cholecystectomy Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized clinical trial compared titanium clips and LigaSure (a vessel sealing device) for controlling bleeding during laparoscopic gallbladder surgery. A total of 114 patients were divided into two equal groups, with one group receiving clips and the other treated using LigaSure. The study found that LigaSure significantly reduced intraoperative blood loss and the time required to achieve hemostasis compared to clips, while overall operative time remained similar in both groups. No major complications were observed. The results suggest that LigaSure provides more efficient and reliable bleeding control, likely due to its advanced mechanism of sealing blood vessels. Although clips remain widely used, LigaSure may be a better option, especially in difficult surgical cases. Overall, the study concludes that LigaSure is a safe and effective alternative to titanium clips with superior hemostatic outcomes in laparoscopic cholecystectomy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07517783
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of clips
Trials testing the same drug.
- NCT03930667 — Closure of the Appendix Stump in Laparoscopic Appendectomy · NA · completed
Other recruiting trials for Laparoscopic Cholecystectomy Surgery
Currently open trials in the same condition.
- NCT07195331 — Comparison Between Standard and Reduced Doses of Indocyanine Green in Fluorescence Cholangiography During Laparoscopic C · Phase 4 · recruiting
- NCT07409688 — Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic · Phase 4 · recruiting
- NCT07019818 — Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intu · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07517783 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wah Medical college , POF hospital
- Last refreshed: 8 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07517783.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing