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NCT07516756: BCP-Skin

Effect of Collagen Peptides on Skin Health: A Clinical Trial

Completed NA Last updated 8 April 2026
What this trial tests

NA trial testing Placebo in Age-related Changes in Skin Appearance and Physiology in 66 participants. Completed in 4 October 2024.

Timeline
8 August 2024
Primary endpoint
4 October 2024
4 October 2024

Quick facts

Lead sponsorCollagen Research Institute
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposeprevention
Enrollment66
Start date8 August 2024
Primary completion4 October 2024
Estimated completion4 October 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Collagen Research Institute

Who can join

Adults 35 to 55, female only, with Age-related Changes in Skin Appearance and Physiology. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to evaluate whether daily oral supplementation with 2.5 g of specific bioactive collagen peptides (SCP) can improve skin physiology in healthy adult women aged 35-55 years. The main questions it aims to answer are: Does SCP supplementation increase skin hydration and barrier function? Does SCP improve skin elasticity, firmness, and collagen content? Does SCP reduce the appearance of periorbital wrinkles and improve overall skin appearance? Researchers will compare SCP supplementation to a placebo (a look-alike substance containing no collagen peptides) to see if SCP supports skin structure and appearance over eight weeks. Participants will: Consume one sachet of SCP or placebo daily for eight weeks Attend three study visits at baseline, week 4, and week 8 for facial imaging, instrumental skin measurements, and expert assessments Have objective measures taken, including skin hydration, transepidermal water loss, elasticity, firmness, dermal collagen content, and 3D wrinkle morphology Complete subjective skin assessments rated by trained evaluators using a visual analogue scale Report any adverse events or intolerance reactions at each visit This study is designed to provide an integrated evaluation of multiple skin parameters, including barrier function, biomechanical properties, dermal matrix composition, and wrinkle characteristics, in a single trial. By combining objective and subjective measures, the study aims to generate robust and clinically interpretable evidence for the effects of oral collagen peptide supplementation on skin health.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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