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NCT07515508: MIRACLE
Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurE
trial in Cardiogenic Shock in 600 participants. Currently enrolling.
31 July 2027
Quick facts
| Lead sponsor | University Heart Center Freiburg - Bad Krozingen |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 600 |
| Start date | 7 August 2024 |
| Primary completion | 31 July 2027 |
| Estimated completion | 31 July 2028 |
| Sites | 4 locations across Germany |
Conditions studied
- Cardiogenic Shock — all drugs for Cardiogenic Shock →
- Acute Heart Failure (AHF) — all drugs for Acute Heart Failure (AHF) →
Sponsor
University Heart Center Freiburg - Bad Krozingen
Who can join
18 and older, any sex, with Cardiogenic Shock or Acute Heart Failure (AHF). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to learn whether information collected during routine hospital care, together with blood and urine samples, can help doctors better identify different types of cardiogenic shock and better predict outcomes in adults hospitalized with acute heart failure and cardiogenic shock. The main question is whether clinical findings, imaging results, and biomarkers, including sex-specific factors, are associated with the risk of death within 30 days. Participants will not receive an experimental treatment. Researchers will collect data from routine care, collect additional blood and urine samples for biobanking, and follow participants after hospital discharge
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07515508
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cardiogenic Shock
Currently open trials in the same condition.
- NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
- NCT07345559 — Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic Shock · NA · recruiting
- NCT07374289 — On Scene ECPR in Ostrava · NA · recruiting
- NCT07402018 — Intra-aortic Balloon Counterpulsation (IABC) Compliance · recruiting
- NCT07309029 — Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR · recruiting
Other University Heart Center Freiburg - Bad Krozingen trials
Trials by the same sponsor.
- NCT07399392 — Radial Versus Femoral Secondary Access in Patients Undergoing TAVI · NA · recruiting
- NCT04192760 — Culotte Versus DK-CRUSH Technique in Non-left Main Coronary Bifurcation Lesions · NA · unknown
- NCT01924962 — Recovery of Left Ventricular Function in Chronic Total Occluded Coronary Arteries · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07515508 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Heart Center Freiburg - Bad Krozingen
- Last refreshed: 7 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07515508.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing