NCT07515196: ESEMP

The Sedative Effects of Music Listening on Pain During Cold Pressor Test

Completed NA Last updated 7 April 2026

What this trial tests

NA trial testing Phase 1 - Silence (Baseline) in Analgesic Effects of Music in 40 participants. Completed in 15 January 2026.

Timeline

14 November 2025

Primary endpoint
15 January 2026

15 January 2026

Quick facts

Lead sponsor	Rawane El Dimachki
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	supportive care
Enrollment	40
Start date	14 November 2025
Primary completion	15 January 2026
Estimated completion	15 January 2026
Sites	1 location across Lebanon

Drugs / interventions tested

• Phase 1 - Silence (Baseline)
• Phase 2 - Happy Mode with Measured Rhythm
• Phase 3 - Sad Mode with Measured Rhythm
• Phase 4 - Happy Mode with Non-Measured Rhythm
• Phase 5 - Sad Mode with Non-Measured Rhythm Type: Behavioral
• Phase 6 - Participant-Selected from Predefined Set
• Phase 7 - Silence (Post-Exposure)
• Phase 8 - Participant's Own Choice

Conditions studied

• Analgesic Effects of Music — all drugs for Analgesic Effects of Music →

Sponsor

Rawane El Dimachki

Who can join

Adults 18 to 35, any sex, with Analgesic Effects of Music. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to understand whether listening to music can reduce pain and anxiety caused by a cold-temperature stimulus in healthy young adults (n = 30). It also seeks to identify which musical and neurocognitive factors can produce a calming, analgesic (reduce pain), and anxiolytic (reduce anxiety) effect.

The main questions it aims to answer are:

* Does music based on universal musical features (such as melodic structure, modal scales, intervals, and tempo) help reduce pain and anxiety, regardless of culture or personal taste?
* Does music that reflects the participant's cultural rhythmic background-especially rhythmic styles from the Levant-change how pain and anxiety are perceived during the cold test?
* Does music selected according to each participant's personal listening habits and musical preferences have a sedative, analgesic, and anxiolytic effect?
* Are the calming effects of music the result of multiple combined factors-universal musical traits, cultural influences, and personal preferences-and how do these factors interact to create an overall therapeutic effect during the cold test?

Participants will:

* Take part in 1 session of 7 or 8 phases of cold pressor test
* Give their feedback in a qualitative questionnaire after each phase
* Answer brief questions about their musical background and preferences

This study aims to deepen our understanding of how musical and neurocognitive elements contribute to the sedative effect of music during care situations, and to support the development of a more precise and personalized musical model for use in dental procedures.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.