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NCT07514234
Optimal Allogeneic PRP Concentration for Oocyte In Vitro Maturation in Women With PCOS
NA trial testing PRP plasma rich platelets in PCOS (Polycystic Ovary Syndrome) in 15 participants. Completed in 9 December 2025.
11 September 2023
Quick facts
| Lead sponsor | Gadjah Mada University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 15 |
| Start date | 5 January 2023 |
| Primary completion | 11 September 2023 |
| Estimated completion | 9 December 2025 |
| Sites | 1 location across Indonesia |
Drugs / interventions tested
- PRP plasma rich platelets — full drug profile →
Conditions studied
- PCOS (Polycystic Ovary Syndrome) — all drugs for PCOS (Polycystic Ovary Syndrome) →
Sponsor
Gadjah Mada University
Who can join
Adults 30 to 41, female only, with PCOS (Polycystic Ovary Syndrome). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In vitro maturation is a long-studied technique used to obtain mature oocytes outside the human body. However, this method can increase the risk of ovarian hyperstimulation syndrome (OHSS), particularly in patients with polycystic ovarian syndrome (PCOS). Culture media supplemented with platelet-rich plasma (PRP) has previously shown promise for improving oocyte maturation. This study examined the potential utility of allogeneic PRP supplementation to increase the maturation of germinal vesicle (GV)-stage oocytes collected from PCOS patients who underwent controlled ovarian stimulation. Supplementation with 5% PRP was found to support oocyte maturation under controlled ovarian stimulation. Further investigations are required to refine the use of PRP without controlled ovarian stimulation in clinical IVM protocols that may be beneficial for PCOS patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07514234
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of PRP plasma rich platelets
Trials testing the same drug.
- NCT05944757 — Compare of PRP Autologous Serum and Autologous Serum by Intrastromal Injection in Different Eye Disease Conditions · NA · unknown
Other recruiting trials for PCOS (Polycystic Ovary Syndrome)
Currently open trials in the same condition.
- NCT07197255 — Transcriptomic Profiling of Cumulus Cells From CAPA-IVM · recruiting
- NCT07159880 — Letrozole Extended vs Traditional Therapy for Ovulation Induction in Women With PCOS (PROLEx-PCOS) · NA · recruiting
- NCT07426146 — Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan · recruiting
- NCT07448272 — Letrozole 5 mg for 10 Days Versus Letrozole 10 mg for 5 Days for Ovarian Stimulation in PCOS · NA · active not recruiting
- NCT06793085 — Pro- and Anti-inflammatory Cytokines in PCOS · recruiting
Other Gadjah Mada University trials
Trials by the same sponsor.
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- NCT07373080 — Brief Culturally Adapted Behavioral Activation Therapy for Adults With Depression in Rural Indonesian Primary Care: A Ty · NA · not yet recruiting
- NCT07349082 — Sensory Block Onset: Epidural vs Dural Puncture Epidural in Cesarean Section · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07514234 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gadjah Mada University
- Last refreshed: 7 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07514234.
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