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NCT07513727: VitC-DePg
Vitamin C for Gingival Depigmentation
NA trial testing Topical Vitamin C ( control Arm) in Gingival Hyperpigmentation in 30 participants. Currently enrolling.
1 May 2026
Quick facts
| Lead sponsor | Al-Azhar University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 29 July 2025 |
| Primary completion | 1 May 2026 |
| Estimated completion | 1 May 2026 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Topical Vitamin C ( control Arm)
- Vitamin C mesotherapy
- Microneedling technique
Conditions studied
- Gingival Hyperpigmentation — all drugs for Gingival Hyperpigmentation →
- Gingival Melanin Pigmentation — all drugs for Gingival Melanin Pigmentation →
Sponsor
Al-Azhar University
Who can join
Adults 20 to 40, any sex, with Gingival Hyperpigmentation or Gingival Melanin Pigmentation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the clinical and histopathological efficacy of topical vitamin C applications using three modalities (topical gel, microneedling , and mesotherapy) in gingival depigmentation. Assessment includes clinical evaluation, CIELAB analysis via DOPI, and histopathological examination (Fontana-Masson staining).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07513727
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07513727 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Al-Azhar University
- Last refreshed: 7 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07513727.
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