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NCT07512310: NIPRESS
Non-Invasive and Invasive Assessment of Heart Filling Pressure
trial in Heart Failure in 623 participants. Completed in 14 March 2024.
14 March 2024
Quick facts
| Lead sponsor | University Hospital, Essen |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 623 |
| Start date | 15 March 2018 |
| Primary completion | 14 March 2024 |
| Estimated completion | 14 March 2024 |
| Sites | 1 location across Germany |
Conditions studied
- Heart Failure — all drugs for Heart Failure →
- Pulmonary Hypertension — all drugs for Pulmonary Hypertension →
- Ventricular Dysfunction, Left — all drugs for Ventricular Dysfunction, Left →
- Ventricular Dysfunction — all drugs for Ventricular Dysfunction →
Sponsor
University Hospital, Essen
Who can join
18 and older, any sex, with Heart Failure or Pulmonary Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study evaluates how different non-invasive and invasive measurements reflect left ventricular filling pressure, an important indicator of cardiac function. Elevated filling pressure is associated with symptoms such as shortness of breath and plays a central role in the diagnosis and management of heart failure and pulmonary hypertension. In clinical practice, filling pressure can be estimated using echocardiography or measured during cardiac catheterisation. However, the relationships between these measurements and their ability to accurately reflect true filling pressure are not fully understood. This retrospective study includes patients who underwent cardiac catheterisation with invasive haemodynamic assessment and temporally related echocardiographic evaluation as part of routine clinical care. The aim is to improve understanding of how different measurements relate to each other and to identify which parameters best reflect elevated filling pressure. The results are expected to support more accurate interpretation of haemodynamic measurements and improve clinical decision-making, particularly regarding the use of non-invasive versus invasive assessment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07512310
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University Hospital, Essen trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07512310 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Essen
- Last refreshed: 6 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07512310.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing