NCT07508774

Simulation and Feasibility Study of Drone-Delivered AED for Out-of-Hospital Cardiac Arrest

Not yet recruiting NA Last updated 2 April 2026

What this trial tests

NA trial testing Drone-Based AED Delivery System in Out-of-Hospital Cardiac Arrest (Simulated) in 24 participants. Not yet recruiting.

Timeline

1 April 2026

Primary endpoint
1 October 2026

1 December 2026

Quick facts

Lead sponsor	Ye Sheng
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	24
Start date	1 April 2026
Primary completion	1 October 2026
Estimated completion	1 December 2026
Sites	1 location across China

Drugs / interventions tested

• Drone-Based AED Delivery System
• Standard Ground Ambulance Response Pathway Simulation

Conditions studied

• Out-of-Hospital Cardiac Arrest (Simulated) — all drugs for Out-of-Hospital Cardiac Arrest (Simulated) →

Sponsor

Ye Sheng

Who can join

Adults 18 to 65, any sex, with Out-of-Hospital Cardiac Arrest (Simulated). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: Survival after out-of-hospital cardiac arrest (OHCA) depends heavily on early defibrillation. Reducing the time from cardiac arrest to defibrillation is a key factor in improving survival. In recent years, many countries have promoted early defibrillation through public automated external defibrillator (AED) networks. However, in practice, public access to and use of AEDs remain limited because of insufficient accessibility, uneven distribution, difficulties in locating devices, and delays in retrieval. With the development of drone technology, rapid drone-based AED delivery has been considered a potentially promising solution. Drones may bypass ground traffic congestion and reach the scene more quickly via aerial routes, allowing bystanders to use an AED under remote guidance. Although simulation studies, system optimization studies, and preliminary real-world applications of drone-delivered AEDs have been reported in other countries, this field remains exploratory in China. At present, most Chinese cities still rely mainly on conventional ambulance dispatch systems and fixed AED networks, both of which may be limited by urban traffic congestion, high population density, and uneven spatial distribution of AEDs.

Objective: This prospective quasi-real-world simulation study in Wuhu, Anhui Province, China, aims to compare the time efficiency of a drone-based AED delivery pathway with that of a standard ground ambulance response pathway in simulated OHCA scenarios. The study will also evaluate the effects of geographic setting, traffic period, and different aerial delivery modes on delivery performance, in order to provide preliminary evidence for the deployment of drone-assisted emergency response networks in Chinese cities.

Methods: This is an open-label, non-randomized, exploratory pilot feasibility study. The drone launch site will be located at a designated takeoff and landing area near the Emergency Department building of the Second Affiliated Hospital of Wannan Medical College. Simulated task endpoints will be selected within a 30-km one-way mission radius from the launch site. The study includes three sub-studies: (1) comparison of response efficiency between the drone pathway and the ground ambulance pathway in urban versus suburban locations; (2) comparison of response efficiency between the drone pathway and the ground ambulance pathway during peak versus off-peak traffic periods; and (3) comparison of operational time and success rate among three drone AED delivery modes, including winch lowering, low-altitude compartment retrieval, and direct landing. A total of 24 healthy volunteers will participate in the simulation tasks, and 1 to 3 professional drone operators will conduct flight operations. For each simulated task, a unified start command will be issued by the study coordinator, and the volunteer will receive the AED and complete electrode pad placement on the manikin.

Primary Outcome: The primary outcome is the time from the unified simulated task start to completion of AED pad placement on the manikin chest.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.