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NCT07504731
Trunk Inclination, Positive End-expiratory Pressure, and Lung Recruitability
trial testing Specific lung recruitment maneuvers and decremental PEEP steps in Acute Respiratory Distress Syndrome (ARDS) in 40 participants. Currently enrolling.
31 March 2027
Quick facts
| Lead sponsor | Zhongda Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 40 |
| Start date | 20 March 2026 |
| Primary completion | 31 March 2027 |
| Estimated completion | 30 April 2027 |
| Sites | 3 locations across China |
Drugs / interventions tested
- Specific lung recruitment maneuvers and decremental PEEP steps
Conditions studied
- Acute Respiratory Distress Syndrome (ARDS) — all drugs for Acute Respiratory Distress Syndrome (ARDS) →
Sponsor
Zhongda Hospital
Who can join
18 and older, any sex, with Acute Respiratory Distress Syndrome (ARDS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This multicenter, physiological, observational study hypothesizes that in moderate to severe ARDS, trunk inclination unloads the chest wall, but its impact on lung mechanics depends on PEEP levels and lung recruitability.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07504731
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Acute Respiratory Distress Syndrome (ARDS)
Currently open trials in the same condition.
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- NCT07123961 — Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial · Phase 2 · recruiting
- NCT06844617 — A Trial of Staff Time With Proned Patients in the ICU Using the 'BathMat' · NA · recruiting
- NCT06967207 — Electrical Impedance Tomography-Based Prognostic Model for ARDS · recruiting
Other Zhongda Hospital trials
Trials by the same sponsor.
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- NCT07311915 — Propranolol Combined With Novel Endocrine Therapy and Androgen Deprivation Therapy (ADT) for Neoadjuvant Treatment in Hi · NA · not yet recruiting
- NCT07585877 — Effect of Branched-Chain Amino Acid Supplementation on Myopia Progression · NA · active not recruiting
- NCT07337980 — A Study on the Safety and Effectiveness of Endoscopic Intracavitary Submucosal Dissection for Gastric Extracavitary-Type · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07504731 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zhongda Hospital
- Last refreshed: 1 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07504731.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing