Last reviewed · How we verify
NCT07503860
Indirect Biomarkers and Exercise Induced Muscle Damage
NA trial testing Eccentric Exercise in Exercise Induced Muscle Damage in 48 participants. Participants enrolled and being followed up; not accepting new ones.
27 November 2025
Quick facts
| Lead sponsor | Vassilis Paschalis |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 48 |
| Start date | 22 August 2025 |
| Primary completion | 27 November 2025 |
| Estimated completion | 15 July 2026 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- Eccentric Exercise
Conditions studied
- Exercise Induced Muscle Damage — all drugs for Exercise Induced Muscle Damage →
Sponsor
Vassilis Paschalis
Who can join
Adults 18 to 30, male only, with Exercise Induced Muscle Damage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to investigate the magnitude of changes in biomarkers of exercise-induced muscle damage following an acute bout of eccentric exercise of the knee extensors performed on an isokinetic dynamometer. Moreover, these biomarkers will be assessed at different time points after the initial intervention, checking the repeated bout effect phenomenon.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07503860
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Eccentric Exercise
Trials testing the same drug.
- NCT07025668 — The Effectiveness of Different Exercise Approaches in Biceps Brachii Long Head Tendinopathy · NA · recruiting
- NCT06573879 — Effect of Eccentric Exercise on Musculus Triceps Surae Muscle Architecture, Muscle Strength, and Performance · NA · completed
- NCT05606276 — Effects of Eccentric Potentiation Activation on Muscle Function · NA · withdrawn
- NCT03264326 — Efficacy of BFR Training Combined With Eccentric Exercise as Assessed by SWE in Subjects With Chronic AT · NA · terminated
- NCT02350465 — Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans · NA · unknown
Other recruiting trials for Exercise Induced Muscle Damage
Currently open trials in the same condition.
- NCT07219498 — Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness · NA · recruiting
- NCT06810271 — Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07503860 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Vassilis Paschalis
- Last refreshed: 31 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07503860.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing