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NCT07499830: OPAL-CAD
Performance of an OCR-Prompt-LLM Integrated Workflow for Extracting Multi-dimensional Clinical Data in Ischemic Heart Disease
trial testing OCR-Prompt-LLM Information Extraction Workflow in Coronary Artery Disease in 308 participants. Completed in 2 March 2026.
1 March 2026
Quick facts
| Lead sponsor | China National Center for Cardiovascular Diseases |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 308 |
| Start date | 23 February 2026 |
| Primary completion | 1 March 2026 |
| Estimated completion | 2 March 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- OCR-Prompt-LLM Information Extraction Workflow
- Manual Clinical Data Review
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
- Artificial Intelligence (AI) — all drugs for Artificial Intelligence (AI) →
- Data Collection — all drugs for Data Collection →
Sponsor
China National Center for Cardiovascular Diseases — full company profile →
Who can join
18 and older, any sex, with Coronary Artery Disease or Artificial Intelligence (AI). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research aims to evaluate a comprehensive AI-driven workflow for both clinical data extraction and diagnostic classification in coronary artery disease (CAD). Leveraging OCR and Large Language Models (LLMs), the system is designed to extract ten key clinical parameters (such as LVEF and lab results) and provide diagnostic subtypes (UA, STEMI, NSTEMI, CCS) directly from unstructured inpatient records. A man-machine comparative trial will be conducted using a test set of 308 patients, where the performance of the LLM-based workflow will be benchmarked against the average diagnostic accuracy and processing time of seven clinical physicians. The findings will provide evidence for the feasibility of using LLMs to enhance clinical data structuring and diagnostic efficiency in cardiology.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07499830
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other China National Center for Cardiovascular Diseases trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07499830 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by China National Center for Cardiovascular Diseases
- Last refreshed: 30 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07499830.
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