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NCT07489807
The Effect of Mild-gain Amplification on Tinnitus Perception in Normal Hearing Adults
NA trial testing Hearing Aid with NR_4 in Tinnitus in 15 participants. Currently enrolling.
1 August 2026
Quick facts
| Lead sponsor | Technical University of Denmark |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 15 |
| Start date | 1 April 2025 |
| Primary completion | 1 August 2026 |
| Estimated completion | 1 June 2027 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Hearing Aid with NR_4 — full drug profile →
Conditions studied
- Tinnitus — all drugs for Tinnitus →
Sponsor
Technical University of Denmark
Who can join
18 and older, any sex, with Tinnitus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigated the effect of mild gain amplification (8dB covering 1 Hz to 8kHz) as tinnitus treatment for participants with normal hearing and compared these effects with an active placebo condition using hearing aids without amplification in a double-blinded crossover study. 12 participants with normal hearing and chronic tinnitus were included in the study. Two different hearing aid treatments were provided for 3 weeks each: mild gain amplification that provided 8dB gain in the frequency range from 1 Hz to 8 kHz and no amplification, acting as placebo. The effect of the two treatments on tinnitus distress was evaluated with the Tinnitus Functional Index (TFI) questionnaire. The effect of the treatment on tinnitus loudness and annoyance were evaluated with a visual analog scale (VAS).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07489807
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Hearing Aid with NR_4
Trials testing the same drug.
- NCT04018911 — Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2019_20 · NA · completed
Other recruiting trials for Tinnitus
Currently open trials in the same condition.
- NCT07393880 — Bimodal Electrical-Sound Stimulation and Auditory Training for Chronic Tonal Tinnitus · NA · recruiting
- NCT07071480 — Noninvasive Therapy for Tinnitus · NA · recruiting
- NCT07435298 — Navigated Repetitive TMS for Chronic Tinnitus · NA · recruiting
- NCT07158034 — Investigating EEG as a Biomarker for Tinnitus Improvement After Bimodal Stimulation · NA · recruiting
- NCT07017998 — External Therapy for Tinnitus Management · NA · recruiting
Other Technical University of Denmark trials
Trials by the same sponsor.
- NCT07026526 — Human Milk Oligosaccharides' Impact on Maturation of the Gut Microbiota · completed
- NCT04314882 — The Danish National Survey of Diet and Physical Activity 2021-2024 · completed
- NCT04593290 — Listen Carefully: An Exploratory Study of the Association Between Listening Effort and Cognitive Function · NA · completed
- NCT05271825 — Broadband Amplification as Tinnitus Treatment · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07489807 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Technical University of Denmark
- Last refreshed: 31 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07489807.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing