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NCT07486765: FundoRing_RY
FundoRing Roux-en-Y Gastric Bypass Versus FundoRing One Anastomosis Gastric Bypass
NA trial testing Laparoscopic FundoRing gastric bypass in Obesity in 200 participants. Completed in 13 March 2026.
12 March 2026
Quick facts
| Lead sponsor | The Society of Bariatric and Metabolic Surgeons of Kazakhstan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 200 |
| Start date | 4 July 2024 |
| Primary completion | 12 March 2026 |
| Estimated completion | 13 March 2026 |
| Sites | 1 location across Kazakhstan |
Drugs / interventions tested
- Laparoscopic FundoRing gastric bypass
Conditions studied
- Obesity — all drugs for Obesity →
- Roux-en-y Anastomosis Site — all drugs for Roux-en-y Anastomosis Site →
- Reflux Gastritis — all drugs for Reflux Gastritis →
- Reflux Esophagitis — all drugs for Reflux Esophagitis →
Sponsor
The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Who can join
Adults 18 to 60, any sex, with Obesity or Roux-en-y Anastomosis Site. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Metabolic and bariatric surgery (MBS) is an effective and durable treatment of severe obesity and its co-morbidities. Gastric bypass is one of the main MBS procedures and is performed using various surgical techniques. The main postoperative bariatric complication after one anastomosis gastric bypass (OAGB) is bile reflux, and the main disadvantage of traditional Roux-en-Y gastric bypass (RYGB) is dumping syndrome. The successful strategies for avoiding reflux esophagitis and other complication following gastric bypass is the use FundoRing method for gastric bypass with creation fundoplication employing the excluded (remnant) part of the stomach. Routine use of a modified fundoplication of the OAGB-excluded stomach to treat patients with obesity decreased acid and prevented bile reflux esophagitis significantly more effectively than standard OAGB. However, the anastomosis after OAGB is constantly bathed in bile. This was previously thought to significantly increase the risk of ulcers, but modern data shows that bile may even have a "protective" buffering effect, neutralizing acid, although the risk of alkaline gastritis remains. The results of trial of consequences of reflux bile flow from the intestine into the gastric pouch after OAGB are controversial. How does this affect the incidence of marginal ulcers due to enterogastric reflux? The answers to these questions remain unclear. The aim of the study was to compare the incidence of distal gastric pouch inflammation and the likelihood of marginal ulcers in patients treated with the FundoRing Roux-en-Y gastric bypass versus the FundoRing OAGB.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07486765
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other The Society of Bariatric and Metabolic Surgeons of Kazakhstan trials
Trials by the same sponsor.
- NCT07495020 — The Laparoscopic Transit Bipartition With Use Metalic Anastomosis Clip · NA · not yet recruiting
- NCT07189416 — The Same-Day and One Day Gastric Bypass by Use the "FundoRing" Method (Same-Day_FundoRing Trial) · NA · completed
- NCT06338969 — The Impact of Different Carbohydrate Restriction After a Gastric Bypass on the Ketosis and Ketoacidosis · NA · recruiting
- NCT04834635 — The FundoRingOAGB Versus Non-wrapping (Non-banded) Standard Method of Laparoscopic One Anastomosis Gastric Bypass · NA · completed
- NCT06176443 — Impact of an Increased Restrictive Factor of One Anastomosis Gastric Bypass on Metabolic Outcomes Type 2 Diabetes. · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07486765 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Society of Bariatric and Metabolic Surgeons of Kazakhstan
- Last refreshed: 20 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07486765.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing