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MATCHING - feMAle geniTal sCHistosomiasis IN miGrants Female Genital Schistosomiasis in Migrants Presenting to an Outpatient Clinic in Italy: Prevalence and Clinical Impact
The aim of this study is to evaluate the prevalence of female genital schistosomiasis (FGS) in the migrant population with gynecological problems who access our center's dedicated outpatient clinic. Furthermore, we will address the relevance of FGS in women with clinical manifestations of the upper genital tract and evaluate the role of cervical-vaginal swabs in predicting upper genital tract involvement in schistosomiasis infection. The study is classified as experimental despite its descriptive objective of the prevalence of the infection of interest, as the vaginal swab and the PCR test performed on the swab and, if necessary, on the histological sample (collected during a possible interventional procedure performed for the patient's clinical needs) are not part of the standard clinical management of these cases but will be performed for the purposes of the study.
Details
| Lead sponsor | IRCCS Sacro Cuore Don Calabria di Negrar |
|---|---|
| Phase | NA |
| Status | RECRUITING |
| Enrolment | 96 |
| Start date | 2025-02-20 |
| Completion | 2027-08 |
Conditions
- Female Genital Schistosomiasis
Interventions
- Cervical-vaginal swab
Primary outcomes
- Female Genital Schistosomiasis (FGS) — At baseline
Proportion of FGS cases, defined as women with the given symptoms/signs and positive real-time PCR on cervical-vaginal swab and/or biopsy over the total number of women tested.
Countries
Italy