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NCT07481695
Retrospective Follow-up Study on Lower Eyelid Melanin and Wrinkles After Blepharoplasty for Lower Eyelid Bags
trial testing transconjunctival lower blepharoplasty in Wrinkle Appearance in 120 participants. Completed in 1 February 2026.
1 September 2025
Quick facts
| Lead sponsor | Peking Union Medical College |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 120 |
| Start date | 1 February 2021 |
| Primary completion | 1 September 2025 |
| Estimated completion | 1 February 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- transconjunctival lower blepharoplasty
- POD lifting
Conditions studied
- Wrinkle Appearance — all drugs for Wrinkle Appearance →
- Melanin Hyperpigmentation — all drugs for Melanin Hyperpigmentation →
Sponsor
Peking Union Medical College
Who can join
35 and older, any sex, with Wrinkle Appearance or Melanin Hyperpigmentation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This observational study aims to investigate the long-term outcomes of transconjunctival lower eyelid blepharoplasty, with a specific focus on changes in lower eyelid hyperpigmentation or hypopigmentation and morphological alterations of wrinkles at short-term and long-term postoperative time points. It further seeks to clarify the overall impact of this surgical approach on lower eyelid skin appearance. The study addresses the following research questions: Does transconjunctival lower eyelid blepharoplasty improve lower eyelid pigmentation? If so, to what extent is the improvement achieved? Does transconjunctival lower eyelid blepharoplasty exacerbate lower eyelid wrinkles? What adjunctive or combined surgical techniques may mitigate this effect? All study participants had previously undergone transconjunctival lower eyelid blepharoplasty for the purpose of periorbital rejuvenation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07481695
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of transconjunctival lower blepharoplasty
Trials testing the same drug.
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Other recruiting trials for Wrinkle Appearance
Currently open trials in the same condition.
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Other Peking Union Medical College trials
Trials by the same sponsor.
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- NCT07109765 — Secukinumab Treatment for Moderate to Severe Hidradenitis Suppurativa · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07481695 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking Union Medical College
- Last refreshed: 19 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07481695.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing