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NCT07476703: SCAPIS-ReEx
Expanded Studies on the SCAPIS Stockholm Reexamination Cohort
trial testing Coronary computer tomography (CCTA) in Coronary Artery Disease in 1,400 participants. Currently enrolling.
30 March 2026
Quick facts
| Lead sponsor | Danderyd Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 1,400 |
| Start date | 8 April 2024 |
| Primary completion | 30 March 2026 |
| Estimated completion | 30 August 2026 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Coronary computer tomography (CCTA)
- Echocardiograhy and aortic ultrasound
- Liver elastography
- Arterial stiffness
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
- Arterial Stiffness, Blood Pressure — all drugs for Arterial Stiffness, Blood Pressure →
- AORTIC VALVE DISEASES — all drugs for AORTIC VALVE DISEASES →
- Mitral Valve Stenosis and/or Insufficiency — all drugs for Mitral Valve Stenosis and/or Insufficiency →
Sponsor
Danderyd Hospital
Who can join
Adults 56 to 74, any sex, with Coronary Artery Disease or Arterial Stiffness, Blood Pressure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018. The study is a collaborative effort among six university hospitals across Sweden. A follow-up study, SCAPIS 2, is conducted for half of the original participants. In Stockholm, 2,500 individuals will be re-examined at Danderyd University Hospital and Karolinska Institutet. SCAPIS 2 includes a core set of examinations involving blood sampling, questionnaires, and imaging. In addition to these, complementary local investigations are conducted to enable more detailed research questions. This protocol describes the additional studies conducted in the Stockholm cohort. All complementary assessments aim to identify risk factors for current and future lung, liver, and cardiovascular diseases.: EXTENDED SAMPLING: Saliva and Blood Samples with Blood Cell Isolation. EXTENDED QUESTIONNAIRES: Dyspnea, Sleep, Respiratory Infections, and Dental Health. EXTENDED IMAGING AND PHYSIOLOGICAL MEASUREMENTS Cardiac Ultrasound and Abdominal Aortic Measurements. Liver Elastography. Vascular Stiffness by cuff-based pulse wave analysis and Photoplethysmography (PPG). Valvular and Vascular Calcification by CT imaging.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07476703
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07476703 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Danderyd Hospital
- Last refreshed: 17 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07476703.
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