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NCT07471061: ALARMS
Acute Ischemic Stroke Involves Significant Inflammatory Response. This Prospective Cohort Study Evaluates the Predictive Value of Monocyte-, Neutrophil-, and Leukocyte-to-albumin Ratios for Stroke Severity and Functional Outcome Using NIHSS at Admission and Modified Rankin Scale During Follow-up.
trial in Acute Ischemic Stroke (AIS) in 60 participants. Not yet recruiting.
1 July 2026
Quick facts
| Lead sponsor | Sohag University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 1 April 2026 |
| Primary completion | 1 July 2026 |
| Estimated completion | 1 October 2026 |
Conditions studied
- Acute Ischemic Stroke (AIS) — all drugs for Acute Ischemic Stroke (AIS) →
Sponsor
Sohag University
Who can join
18 and older, any sex, with Acute Ischemic Stroke (AIS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Acute Ischemic Stroke is a leading cause of mortality and long-term disability worldwide. Increasing evidence suggests that systemic inflammation plays a significant role in the pathophysiology and progression of ischemic brain injury. Recently, several inflammatory biomarkers derived from routine laboratory tests have been investigated as potential predictors of stroke severity and clinical outcome. This prospective cohort study aims to evaluate the predictive utility of the monocyte-to-albumin ratio, neutrophil-to-albumin ratio, and total leukocytic count-to-albumin ratio in patients with acute ischemic stroke. These indices combine inflammatory cell counts with serum albumin levels and may reflect both systemic inflammatory status and nutritional condition. Stroke severity will be assessed at admission using the NIH Stroke Scale, while functional outcome will be evaluated during follow-up using the Modified Rankin Scale. The study aims to determine whether these simple and readily available biomarkers can serve as reliable predictors of stroke severity and prognosis in patients with acute ischemic stroke.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07471061
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Related trials
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Currently open trials in the same condition.
- NCT06210633 — Prospective Registry of Endovascular Thrombectomy for eXtra-Large Ischemic Stroke · recruiting
Other Sohag University trials
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- NCT07515365 — Colitis Patterns in Patients With Lower GI Symptoms · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07471061 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sohag University
- Last refreshed: 17 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07471061.
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