Last reviewed · How we verify
NCT07466849: EIB-H
Hypoxic Environment on EIB and Performance in Race Walkers
trial testing High-Altitude Training & Hypoxic Environment Exposure in Exercise-induced Bronchoconstriction (EIB) in 64 participants. Completed in 18 October 2025.
16 October 2025
Quick facts
| Lead sponsor | Shanghai University of Sport |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 64 |
| Start date | 16 July 2025 |
| Primary completion | 16 October 2025 |
| Estimated completion | 18 October 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- High-Altitude Training & Hypoxic Environment Exposure
Conditions studied
- Exercise-induced Bronchoconstriction (EIB) — all drugs for Exercise-induced Bronchoconstriction (EIB) →
Sponsor
Shanghai University of Sport
Who can join
18 and older, any sex, with Exercise-induced Bronchoconstriction (EIB). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Title: Diagnosis and Impact of Exercise-Induced Bronchoconstriction (EIB) in Athletes During Altitude Training Study Description: We invite you to participate in a research study examining Exercise-Induced Bronchoconstriction (EIB) in athletes. Your participation is entirely voluntary, and you may withdraw at any time without penalty. This study will take place over 2 to 4 months and includes both plains training and altitude training phases. Why is this study being done? The purpose of this study is threefold: To diagnose whether you have EIB (a condition that causes narrowing of the airways during or after exercise). To determine if altitude training induces or worsens EIB. To understand how having (or not having) EIB affects your athletic performance during altitude training. What will you be asked to do? You will be asked to complete the following procedures four times each (with about 2 weeks between each session): Blood Draws: Early morning fasting blood samples (approx. 4 ml from your arm). These are routine tests for the sports team. Exercise Challenge Tests: You will run on a treadmill while wearing a heart rate monitor. This test follows standard safety guidelines (ATS). Your breathing will be tested before exercise and several times after. These are routine tests for the sports team. VO2max Tests: You will run on a treadmill with a breathing mask to measure your maximum oxygen uptake. You will run until exhaustion, following a standardized protocol. Questionnaires: You will wear a heart rate monitor during training and complete short questionnaires about your breathing and how hard you feel you are exercising. How long will participation last? The total study duration is 2-4 months. Individual tasks take between 3 minutes (blood draw) and 50 minutes (exercise challenge). What are the risks? Blood Draw: Possible dizziness, bruising, or discomfort at the needle site. Breathing Tests: You may feel briefly dizzy or tired from blowing hard; this passes quickly. Chest pain is very rare. Exercise Tests: You will experience muscle fatigue and soreness. If you have EIB, you may feel short of breath, wheeze, or feel chest tightness. If symptoms become severe, the test will be stopped. Salbutamol (a standard asthma medication) may be given to relieve symptoms. Using salbutamol as described in this study is permitted under WADA anti-doping rules. What are the benefits? If you do not have EIB, you will receive an educational booklet on preventing EIB. If you do have EIB, you will receive a detailed report for your coach, personalized strategies, and long-term follow-up support. Compensation: If you complete the entire study, you will receive a commemorative gift. No compensation is provided for partial participation. Contact for Questions: If you have any questions about the study or your rights as a participant, please contact the principal investigator listed on the consent form or email the Shanghai Sports University Research Ethics Committee at lunli@sus.edu.cn.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07466849
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Shanghai University of Sport trials
Trials by the same sponsor.
- NCT07519798 — Effects of Transcranial Temporal Interference Stimulation on Cognitive Function in Mild Cognitive Impairment · NA · enrolling by invitation
- NCT07488715 — High-Intensity Interval Training Across Exercise Environments: Acute Effects on Physiological Stress, Cardiovascular Res · NA · not yet recruiting
- NCT07494552 — Running Environments on Physiological Responses, Emotion, Motivation, and Attention · NA · not yet recruiting
- NCT07518290 — Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease · NA · recruiting
- NCT07309198 — Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07466849 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shanghai University of Sport
- Last refreshed: 12 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07466849.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing