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NCT07462546
Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)
NA trial testing Transcranial Doppler in Artery Stenosis in 232 participants. Currently enrolling.
30 November 2026
Quick facts
| Lead sponsor | General Hospital of Shenyang Military Region |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 232 |
| Start date | 24 March 2026 |
| Primary completion | 30 November 2026 |
| Estimated completion | 30 November 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Transcranial Doppler
Conditions studied
- Artery Stenosis — all drugs for Artery Stenosis →
Sponsor
General Hospital of Shenyang Military Region
Who can join
40 and older, any sex, with Artery Stenosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Carotid artery stenting (CAS) prevents stroke but carries risks of perioperative cerebral embolism. Transcranial Doppler (TCD) ultrasound can detect microemboli during CAS and may offer therapeutic benefits through ultrasound-enhanced thrombolysis. Trials like SONOBUSTER and SONOBIRDIE suggest TCD reduces new brain infarctions during carotid procedures. The TCD-ICAS trial will investigate whether TCD application during and after CAS reduces perioperative cerebral emboli and improves outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07462546
- Europe PMC full search
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Related trials
Other trials of Transcranial Doppler
Trials testing the same drug.
- NCT05144451 — Transcranial Doppler During Liver Transplantation · NA · unknown
- NCT05151978 — Transcranial Doppler in Mild and Moderate Traumatic Brain Injury (TBI) · unknown
- NCT04846738 — Transcranial Doppler and Quantitative Pupillometry as Neurological Prognostic Factors in Brain Damaged Patients Admitted · completed
- NCT04583163 — Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients · terminated
- NCT04154865 — Exercise in Adolescents With Insulin Resistance · NA · terminated
Other recruiting trials for Artery Stenosis
Currently open trials in the same condition.
- NCT07187596 — Mortality Outcome of Controlled Hypertension · active not recruiting
- NCT05550077 — Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis · recruiting
Other General Hospital of Shenyang Military Region trials
Trials by the same sponsor.
- NCT07375953 — Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) · Phase 2 · recruiting
- NCT07375966 — Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours · Phase 2 · recruiting
- NCT07294885 — Deep Cervical LymphatIc-Venous Anastomosis for Alzheimer's Disease · NA · recruiting
- NCT07412249 — Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis · NA · recruiting
- NCT07283159 — Tenecteplase Plus Urinary Kallidinogenase for Acute Ischemic Stroke (TUKIS) · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07462546 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by General Hospital of Shenyang Military Region
- Last refreshed: 25 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07462546.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing