NCT07458867 (IMPEL) is a clinical trial in Large Bowel Obstruction, sponsored by European Society for Trauma and Emergency Surgery.

Who is sponsoring NCT07458867?

NCT07458867 is sponsored by European Society for Trauma and Emergency Surgery.

What condition does NCT07458867 study?

NCT07458867 studies Large Bowel Obstruction.

Is NCT07458867 still recruiting?

NCT07458867 is currently not yet recruiting. Last updated 9 March 2026.

Last reviewed 2026-03-09 · How we verify

NCT07458867: IMPEL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes

Not yet recruiting Last updated 9 March 2026

What this trial tests

trial in Large Bowel Obstruction in 500 participants. Not yet recruiting.

Timeline

1 July 2026

Primary endpoint
30 June 2027

31 July 2027

Quick facts

Lead sponsor	European Society for Trauma and Emergency Surgery
Status	Not yet recruiting
Study type	OBSERVATIONAL
Enrollment	500
Start date	1 July 2026
Primary completion	30 June 2027
Estimated completion	31 July 2027

Conditions studied

Large Bowel Obstruction — all drugs for Large Bowel Obstruction →

Sponsor

European Society for Trauma and Emergency Surgery

Who can join

18 and older, any sex, with Large Bowel Obstruction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare systems. Evidence guiding optimal management remains limited and is largely derived from retrospective or single-center studies. IMPEL is an international, multicenter, time-bound, prospective observational cohort study designed to characterize real-world presentation, diagnostic pathways, operative and non-operative management, and short-term outcomes in adults presenting with mechanical large-bowel obstruction. By capturing standardized patient-level, radiologic, operative, and outcome data across diverse acute care settings, IMPEL aims to describe contemporary practice patterns, quantify variation in care, and identify factors associated with morbidity, mortality, and stoma-related outcomes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other European Society for Trauma and Emergency Surgery trials

Trials by the same sponsor.

NCT07107555 — Necrotizing Soft Tissue Infections · enrolling by invitation
NCT05843097 — SnapSBO - Small Bowel Obstruction Snapshot Audit · completed
NCT03610308 — ESTES Snapshot Audit 2018 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07458867 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by European Society for Trauma and Emergency Surgery
Last refreshed: 9 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07458867.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing