Last reviewed · How we verify
NCT07457047
Effects of Aerobic and Resistance Exercise on Cardiovascular Biomarkers in Sedentary Women
NA trial testing Aerobic Exercise Training in Sedentary Lifestyle in 45 participants. Completed in 1 May 2025.
23 November 2023
Quick facts
| Lead sponsor | Ondokuz Mayıs University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 45 |
| Start date | 22 January 2023 |
| Primary completion | 23 November 2023 |
| Estimated completion | 1 May 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Aerobic Exercise Training
- Resistance Exercise Training
Conditions studied
- Sedentary Lifestyle — all drugs for Sedentary Lifestyle →
- Cardiometabolic Risk — all drugs for Cardiometabolic Risk →
Sponsor
Ondokuz Mayıs University
Who can join
Adults 18 to 25, female only, with Sedentary Lifestyle or Cardiometabolic Risk. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial investigated the effects of aerobic and resistance exercise on cardiovascular and inflammatory biomarkers in sedentary young women. Forty-five healthy sedentary females aged 18 to 25 years were randomly assigned to aerobic exercise, resistance exercise, or control groups. The exercise groups trained three times per week for 8 weeks under supervision, while the control group maintained a sedentary lifestyle. Blood samples and physiological measurements were obtained at baseline and after the intervention. The primary aim was to evaluate changes in circulating natriuretic peptides and inflammatory biomarkers, including NT-proBNP, BNP, soluble ST2, and Galectin-3. Secondary outcomes included lipid profile, glucose and insulin levels, blood pressure, and aerobic fitness. The study examined whether different exercise modalities induce beneficial cardiometabolic adaptations in previously sedentary young women.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of aerobic and resistance exercises on cardiovascular biomarkers in sedentary females: a randomized controlled trial.
Ghadamyari N, Şahin FN, Küçük H. · · 2026 · PMID 42174721 · DOI 10.1186/s13102-026-01754-1
Verify or expand the search:
- PubMed search for NCT07457047
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Aerobic Exercise Training
Trials testing the same drug.
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- NCT06912984 — Heterogeneity of Vascular Adaptations to Exercise With Aging in Women and Men · NA · recruiting
- NCT06970457 — The Interaction of Body Composition, Sex Hormones and Exercise in Men · NA · recruiting
- NCT06126874 — Additional Effects of Aerobic and Resistance Exercises to Pelvic Floor Muscle Training After Radical Prostatectomy · NA · unknown
- NCT04816006 — Breast Cancer, Reasoning, and Activity Intervention · NA · recruiting
Other recruiting trials for Sedentary Lifestyle
Currently open trials in the same condition.
- NCT03511352 — Sedentary Behavior Interrupted: A Trial of Acute Effects on Biomarkers of Healthy Aging · NA · active not recruiting
- NCT03356262 — The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort · active not recruiting
Other Ondokuz Mayıs University trials
Trials by the same sponsor.
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- NCT07525557 — Kinesiophobia, Pain and Disability in Chronic Neck Pain · recruiting
- NCT07497802 — Mindfulness-Based Psychoeducation for Women With Gynecological Cancer · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07457047 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ondokuz Mayıs University
- Last refreshed: 9 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07457047.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing