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NCT07452588: keratitis
Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious Keratitis
NA trial testing Sodium chloride 5% solution in Infectious Keratitis in 40 participants. Not yet recruiting.
1 August 2026
Quick facts
| Lead sponsor | Sohag University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 February 2026 |
| Primary completion | 1 August 2026 |
| Estimated completion | 1 February 2027 |
Drugs / interventions tested
- Sodium chloride 5% solution
- quinolones — full drug profile →
Conditions studied
- Infectious Keratitis — all drugs for Infectious Keratitis →
- Adjuvant Treatment Bacterial Infectious Keratitis — all drugs for Adjuvant Treatment Bacterial Infectious Keratitis →
- Sodium Chloride 5% Solution — all drugs for Sodium Chloride 5% Solution →
Sponsor
Sohag University
Who can join
Adults 18 to 60, any sex, with Infectious Keratitis or Adjuvant Treatment Bacterial Infectious Keratitis. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Control of infection
Time frame: 6 months
Improvement of manifestation according to rate of healing
Sponsor's own description
This study aims to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07452588
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Infectious Keratitis
Currently open trials in the same condition.
- NCT06364878 — Non-invasive Diagnostics of Microbial Keratitis · recruiting
- NCT05888987 — Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection · recruiting
Other Sohag University trials
Trials by the same sponsor.
- NCT07119905 — Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patie · not yet recruiting
- NCT07512219 — Comparison Between Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine · NA · not yet recruiting
- NCT07519694 — Comparative Study Between Different Additives to Lidocaine 2٪ for Peribulbar Block in Vitreoretinal Surgery · NA · not yet recruiting
- NCT07515365 — Colitis Patterns in Patients With Lower GI Symptoms · not yet recruiting
- NCT07523386 — Compartive Study Between Cannulated Screw and Kws in Fixation of Distal Radius · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07452588 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sohag University
- Last refreshed: 2 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07452588.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing