Last reviewed · How we verify
NCT07452562: NECTAR-MS
Hesperidin RCT in MS
NA trial testing Hesperidin in Multiple Sclerosis in 60 participants. Currently enrolling.
18 January 2027
Quick facts
| Lead sponsor | Swansea University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 7 January 2026 |
| Primary completion | 18 January 2027 |
| Estimated completion | 18 January 2027 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Hesperidin — full drug profile →
- Placebo
Conditions studied
- Multiple Sclerosis — all drugs for Multiple Sclerosis →
Sponsor
Swansea University
Who can join
18 and older, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a randomised, double-blind, placebo-controlled trial investigating the effects of Hesperidin supplementation on cognitive function, fatigue, and stress. Participants will be randomly assigned to receive either 500mg of Hesperidin or a matching placebo daily for 12 weeks. The primary outcome is fatigue, with secondary outcomes including cognitive performance and mood. The trial seeks to determine if this dietary intervention offers symptom-alleviating benefits.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07452562
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Hesperidin
Trials testing the same drug.
- NCT06402032 — Clinical and Histological Evaluation of Hesperidin as a Direct Pulp Capping Material · NA · completed
- NCT04316390 — Influence of Hesperidin and Vitamin C on Uric Acid Concentration · NA · completed
- NCT04715932 — Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN) · Phase 2 · completed
- NCT03377140 — The Effects of Hesperidin on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease · NA · unknown
Other recruiting trials for Multiple Sclerosis
Currently open trials in the same condition.
- NCT07507084 — The Effect of Internal- or External-Focused Exercise Training, Administered in Conjunction With a Cognitive Task, on Wal · NA · recruiting
- NCT07524231 — Evaluation of the Effects of Laughter Yoga · NA · recruiting
- NCT07489794 — URINARY INCONTINENCE AND PELVIC FLOOR MUSCLE ACTIVITY IN MULTIPLE SCLEROSIS · recruiting
- NCT07236684 — Identification of Factors Related to UI in Patients With MS and EMG Assessment of PFM Activity · recruiting
- NCT07500727 — Skeletal Muscle Aging and Responsiveness in Aged People With MS · NA · recruiting
Other Swansea University trials
Trials by the same sponsor.
- NCT07272096 — ACTing Minds: An ACT-based Videogame for Mental Health · NA · completed
- NCT06961513 — Patient Evaluation of Treatment of Pelvic-floor Muscle Dysfunction. · not yet recruiting
- NCT06698588 — Symptom-specific Effects of Omega-3 Across Neurodevelopmental Symptoms · NA · recruiting
- NCT06407557 — Optimizing Older Adults' Home Space for Physical Activity · NA · completed
- NCT05591573 — The Impact of Glycemic Index on Sleep and Memory Consolidation · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07452562 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Swansea University
- Last refreshed: 5 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07452562.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing