NCT07448753 (CIPO_GEN) is a clinical trial in Pseudo Obstruction, sponsored by Marina Coletta.

Who is sponsoring NCT07448753?

NCT07448753 is sponsored by Marina Coletta.

What condition does NCT07448753 study?

NCT07448753 studies Pseudo Obstruction.

Is NCT07448753 still recruiting?

NCT07448753 is currently enrolling by invitation. Last updated 5 March 2026.

Last reviewed 2026-03-05 · How we verify

NCT07448753: CIPO_GEN

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

ACTG2/FLNA Testing Yield in Adult Idiopathic Chronic Intestinal Pseudo-Obstruction (CIPO) With Reduced/Absent Distal Esophageal Contractility

ENROLLING BY INVITATION Last updated 5 March 2026

What this trial tests

trial in Pseudo Obstruction in 20 participants. Enrolling by invitation.

Timeline

17 September 2025

Primary endpoint
30 September 2026

30 January 2027

Quick facts

Lead sponsor	Marina Coletta
Status	ENROLLING BY INVITATION
Study type	OBSERVATIONAL
Enrollment	20
Start date	17 September 2025
Primary completion	30 September 2026
Estimated completion	30 January 2027
Sites	1 location across Italy

Conditions studied

Pseudo Obstruction — all drugs for Pseudo Obstruction →

Sponsor

Marina Coletta

Who can join

18 and older, any sex, with Pseudo Obstruction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To assess the diagnostic yield of Sanger sequencing for ACTG2 and FLNA genes evaluation on blood or saliva sample in patients with idiopathic CIPO in which high-resolution esophageal manometry (HRM) shows reduced (DCI \<450 mmHg\*s\*cm) or absent distal esophageal contractility.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07448753 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Marina Coletta
Last refreshed: 5 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07448753.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing