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NCT07446881: B06
A Phase 1 Study, to Evaluate the Effect of ADV7103 on Gastric pH Under Fed and Fasting Conditions in Adult Healthy Participants.
Phase 1 trial testing ADV7103 in EFFECT OF ADV7103 ON GASTRIC PH in 12 participants. Completed in 15 March 2025.
15 March 2025
Quick facts
| Lead sponsor | Advicenne Pharma |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 12 |
| Start date | 25 February 2025 |
| Primary completion | 15 March 2025 |
| Estimated completion | 15 March 2025 |
| Sites | 1 location across France |
Drugs / interventions tested
- ADV7103 — full drug profile →
Conditions studied
- EFFECT OF ADV7103 ON GASTRIC PH — all drugs for EFFECT OF ADV7103 ON GASTRIC PH →
- Distal Renal Tublular Acidosis — all drugs for Distal Renal Tublular Acidosis →
Sponsor
Advicenne Pharma — full company profile →
Who can join
Adults 18 to 45, any sex, with EFFECT OF ADV7103 ON GASTRIC PH or Distal Renal Tublular Acidosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This was a Phase 1, single-center, randomized, controlled, Latin-square, open-label study to evaluate the effect of ADV7103 on the gastric pH, after administering a single oral dose of ADV7103 in healthy adult participants under fasting and fed conditions
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07446881
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of ADV7103
Trials testing the same drug.
- NCT04147871 — Study Evaluating Patients With Cystinuria and Efficacy and Safety Exploratory Study in the Youngest Children · Phase 2, PHASE3 · withdrawn
- NCT03644706 — Study Evaluating Subjects With Distal Renal Tubular Acidosis · Phase 3 · terminated
Other Advicenne Pharma trials
Trials by the same sponsor.
- NCT04147871 — Study Evaluating Patients With Cystinuria and Efficacy and Safety Exploratory Study in the Youngest Children · Phase 2, PHASE3 · withdrawn
- NCT03644706 — Study Evaluating Subjects With Distal Renal Tubular Acidosis · Phase 3 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07446881 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Advicenne Pharma
- Last refreshed: 10 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07446881.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing