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NCT07446634: OSAS
Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome
NA trial testing Maxillomandibular advancement surgery with counterclockwise rotation in Sleep Apnea, Obstructive in 48 participants. Currently enrolling.
30 June 2031
Quick facts
| Lead sponsor | Jani Talvilahti |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 48 |
| Start date | 6 February 2014 |
| Primary completion | 30 June 2031 |
| Estimated completion | 30 June 2032 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Maxillomandibular advancement surgery with counterclockwise rotation
Conditions studied
- Sleep Apnea, Obstructive — all drugs for Sleep Apnea, Obstructive →
Sponsor
Jani Talvilahti
Who can join
Adults 18 to 70, any sex, with Sleep Apnea, Obstructive. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study looks at how jaw surgery called maxillomandibular advancement with counterclockwise rotation affects breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot tolerate standard treatments such as Continous Positive Airway pressure treatment. The participants are followed over time to see whether the surgery improves sleep apnea symptoms, daytime sleepiness, and airway size, and whether these improvements last. Advanced three-dimensional imaging and airflow analysis are used to better understand how the surgery changes the airway and breathing. The goal is to evaluate the long-term effectiveness and safety of this surgical treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07446634
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT06848647 — Treatment of Sleep Apnea to Improve Metabolic Health · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07446634 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jani Talvilahti
- Last refreshed: 3 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07446634.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing