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NCT07440095
Mortality Predictors in Patients 80+ After Major Abdominal Surgery: Role of Frailty and Physiological Reserve
trial testing Major Abdominal Surgery and Frailty Assessment in Frailty in 200 participants. Not yet recruiting.
1 April 2026
Quick facts
| Lead sponsor | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 1 March 2026 |
| Primary completion | 1 April 2026 |
| Estimated completion | 10 April 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Major Abdominal Surgery and Frailty Assessment
Conditions studied
- Frailty — all drugs for Frailty →
- Postoperative Complications — all drugs for Postoperative Complications →
- Aged, 80 and Over — all drugs for Aged, 80 and Over →
- Abdomen Cancer — all drugs for Abdomen Cancer →
Sponsor
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Who can join
80 and older, any sex, with Frailty or Postoperative Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to identify independent risk factors for 30-day mortality in patients aged 80 and over who have undergone major abdominal surgery. While traditional risk scoring systems often focus on chronic disease burden, they may not fully capture the biological decline associated with aging. This research specifically focuses on the predictive value of "frailty" and "physiological reserve" in determining surgical outcomes for this "old-old" patient population. In this retrospective cohort study, data from approximately 200 patients treated between 2022 and 2025 will be analyzed. Frailty will be assessed using the Modified Frailty Index (mFI-5), and physiological reserve will be evaluated through preoperative laboratory markers such as albumin, creatinine, and lymphocyte counts. By determining how these factors influence postoperative mortality, the study aims to improve preoperative patient selection, enhance risk communication with families, and provide a basis for protective strategies like prehabilitation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07440095
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07440095 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07440095.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing