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NCT07438288: SoLiDaRity
Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis
trial testing Observation in Cirrhosis and Chronic Liver Disease in 2,200 participants. Currently enrolling.
12 August 2027
Quick facts
| Lead sponsor | Singapore General Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 2,200 |
| Start date | 12 August 2022 |
| Primary completion | 12 August 2027 |
| Estimated completion | 12 August 2032 |
| Sites | 3 locations across Singapore |
Drugs / interventions tested
- Observation
Conditions studied
- Cirrhosis and Chronic Liver Disease — all drugs for Cirrhosis and Chronic Liver Disease →
Sponsor
Singapore General Hospital
Who can join
18 and older, any sex, with Cirrhosis and Chronic Liver Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to identify factors that predict the development of decompensation, acute-on-chronic liver failure (ACLF) and death in patients with liver cirrhosis. Clinical data will be retrieved from existing hospital records. This information may help doctors to identify patients with cirrhosis who are at risk of deterioration earlier (before they develop complications) and to develop effective treatment strategies to prevent or delay these complications. This study is designed as a prospective, non-interventional, observational study. This means that if you agree to participate in the study, you will not be required to undergo any additional hospital visits, tests, procedures or interventions other than the usual standard-of-care management that your doctor will provide. If you consent to participate in this study, you will be providing the study investigators permission to review and analyse your clinical data from the hospital clinical records. Your data will be collected throughout the course of your disease until liver transplantation or death.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07438288
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Cirrhosis and Chronic Liver Disease
Currently open trials in the same condition.
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Other Singapore General Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07438288 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Singapore General Hospital
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07438288.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing