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NCT07432672
Children With Congenital Diaphragmatic Hernia and the Quality of Their Daily Lives
trial in Congenital Diaphragmatic Hernia in 80 participants. Completed in 1 July 2025.
1 July 2025
Quick facts
| Lead sponsor | Medical University of Vienna |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 1 May 2023 |
| Primary completion | 1 July 2025 |
| Estimated completion | 1 July 2025 |
| Sites | 1 location across Austria |
Conditions studied
- Congenital Diaphragmatic Hernia — all drugs for Congenital Diaphragmatic Hernia →
Sponsor
Medical University of Vienna
Who can join
Adults 5 to 18, any sex, with Congenital Diaphragmatic Hernia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: Congenital diaphragmatic hernia is a rare disease, resulting from a developmental malformation of the diaphragm. Over the last years, management of the affected children has improved significantly. Despite progress in the treatment, it is still related to a high mortality rate. After birth, congenital diaphragmatic hernias are associated with lung hypoplasia as well as pulmonary hypertension which can in turn lead to cardiac dysfunction. Comorbidities as gastroesophageal reflux or respiratory difficulties, such as chronic pulmonary symptoms or repeated respiratory tract infections are common amongst survivors. However, little is known about the health-related quality of life in children after surgical intervention of their diaphragm. Aim: This study aims to obtain information on the health-related quality of life in children with congenital diaphragmatic hernia to improve their future long-term management. Methods: A single-centre prospective study was conducted, examining health-related quality of life of children between five and 18 years of age who were initially treated at the General Hospital of Vienna for congenital diaphragmatic hernia between 2005 and 2019. The validated KIDSCREEN-27 questionnaire was used to assess the health-related quality of life of children with a congenital diaphragmatic hernia, completed by the whole family, including the affected child himself (≥ 8 years old), parents, and siblings. Additionally, a detailed demographic review was obtained.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07432672
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Related trials
Other recruiting trials for Congenital Diaphragmatic Hernia
Currently open trials in the same condition.
- NCT05213676 — De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia · Phase 4 · recruiting
- NCT07187206 — Safety and Efficacy of FETO in CDH Phase III · Phase 3 · recruiting
- NCT07166172 — Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH · NA · recruiting
- NCT06739356 — North American Fetal Therapy Network for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe · NA · recruiting
- NCT03138863 — Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO) · NA · recruiting
Other Medical University of Vienna trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07432672 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University of Vienna
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07432672.
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