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NCT07432009: ORTOPODCZ
Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic
trial in Frailty in 400 participants. Not yet recruiting.
31 December 2029
Quick facts
| Lead sponsor | Tomas Bata Hospital, Czech Republic |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 400 |
| Start date | 1 April 2026 |
| Primary completion | 31 December 2029 |
| Estimated completion | 31 March 2030 |
| Sites | 7 locations across Czechia |
Conditions studied
- Frailty — all drugs for Frailty →
- Cognitive Impairment — all drugs for Cognitive Impairment →
- Older Adults — all drugs for Older Adults →
- Hip Arthroplasty — all drugs for Hip Arthroplasty →
Sponsor
Tomas Bata Hospital, Czech Republic
Who can join
65 and older, any sex, with Frailty or Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This multicenter, prospective, non-interventional observational study (ORTOPODCZ) investigates the association between preoperative cognitive impairment and postoperative delirium (POD) in older adults undergoing elective total hip arthroplasty in the Czech Republic. Postoperative delirium is a frequent and serious neurocognitive complication in senior surgical patients and is associated with increased morbidity, mortality, prolonged hospitalization, and impaired functional and cognitive outcomes. Despite international recommendations, routine preoperative cognitive screening remains insufficiently implemented. The study evaluates the predictive value of the ALBA test, a brief cognitive screening tool, performed during the pre-anesthetic assessment. Postoperative delirium will be assessed using the validated CAM-ICU instrument for up to 72 hours after surgery. Secondary objectives include assessing the relationship between POD and frailty, polypharmacy, comorbidities, type of anesthesia, intraoperative hemodynamics, blood loss, vasoactive support, and postoperative complications. Approximately 300-400 participants aged ≥65 years will be enrolled across seven centers. No additional procedures, biological sampling, or deviations from standard clinical care are required. Data will be collected in REDCap and analyzed according to a predefined statistical analysis plan. The study aims to provide robust evidence supporting the integration of cognitive screening into routine preoperative evaluation and to describe feasibility and implementation requirements for the ALBA test in clinical practice.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07432009
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
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Other Tomas Bata Hospital, Czech Republic trials
Trials by the same sponsor.
- NCT07457814 — Postoperative Pain and Analgesic Use After Total Knee Arthroplasty · not yet recruiting
- NCT07022210 — Incidence of Hypotension in the Post-anesthesia Care Unit (PACU). · recruiting
- NCT06896643 — Urinary Infection and Colonization in Bone Procedures · recruiting
- NCT06869876 — Ortopod CZ Pilot Study · completed
- NCT07481994 — Changes in Value-Based Assessment in Patients Undergoing Major Oncological Surgery · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07432009 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tomas Bata Hospital, Czech Republic
- Last refreshed: 25 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07432009.
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