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NCT07424729
Minimal-flow Anesthesia and Cognitive Outcomes in Elderly Surgical Patients
NA trial testing Mini-Mental State Examination in Postoperative Cognitive Dysfunction in 90 participants. Completed in 15 March 2026.
12 March 2026
Quick facts
| Lead sponsor | Ankara Etlik City Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 90 |
| Start date | 3 October 2025 |
| Primary completion | 12 March 2026 |
| Estimated completion | 15 March 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Mini-Mental State Examination
Conditions studied
- Postoperative Cognitive Dysfunction — all drugs for Postoperative Cognitive Dysfunction →
Sponsor
Ankara Etlik City Hospital
Who can join
Adults 65 to 85, any sex, with Postoperative Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Purpose: Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients following major surgery and is associated with impaired attention, memory, and executive functions. Advanced age and prolonged surgical duration are among the most important risk factors. Minimal flow anesthesia has been suggested to reduce postoperative cognitive impairment by providing more stable anesthetic depth and reducing physiological stress. The aim of this study is to investigate the relationship between surgical duration and postoperative cognitive dysfunction in elderly patients undergoing surgery under minimal flow anesthesia.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07424729
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mini-Mental State Examination
Trials testing the same drug.
- NCT06768112 — Non-Invasive Vagus Nerve Stimulation Combine Postural Training in the Elderly · NA · active not recruiting
Other recruiting trials for Postoperative Cognitive Dysfunction
Currently open trials in the same condition.
- NCT07113483 — Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery · Phase 3 · recruiting
- NCT07452367 — Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery · recruiting
- NCT07000461 — Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass · recruiting
- NCT06689137 — Effects of Dexmedetomidine on Postoperative Neurocognitive Disorder · active not recruiting
- NCT06658769 — Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly · NA · recruiting
Other Ankara Etlik City Hospital trials
Trials by the same sponsor.
- NCT07472452 — MULTIMODAL APPROACH IN THE DIAGNOSIS OF SEPTIC AKI · not yet recruiting
- NCT07488442 — Efficacy of Cognitive Behavioral Therapy Administered in Patients With Dyssynergic Defecation · NA · recruiting
- NCT07488455 — Effectiveness of Video-Based or Written Pelvic Floor Education in Postpartum Women · NA · recruiting
- NCT07375173 — ORI-Guided FiO₂ Titration in Prone Spine Surgery: Impact on Postoperative Atelectasis Assessed by Lung Ultrasound · NA · not yet recruiting
- NCT07456202 — Menstrual Status, Anesthetic Consumption, and PONV · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07424729 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ankara Etlik City Hospital
- Last refreshed: 18 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07424729.
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